ArticleFrontiers in cardiovascular medicine2022
Prognostic Impact of Multiple Lymphocyte-Based Inflammatory Indices in Acute Coronary Syndrome Patients.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 4 of them syntheses that pooled it.
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Who cites it
110 citing papers in PubMed, 4 syntheses or guidelines pooled it, 132 citations in OpenAlex.
- Prognostic value of systemic inflammation response index in patients with myocardial infarction: a systematic review and meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Platelet-To-Lymphocyte Ratio Efficiency in Predicting Major Adverse Cardiovascular Events After Percutaneous Coronary Intervention in Acute Coronary Syndromes: A Meta-Analysis.Reviews in cardiovascular medicine · 2025Pooled it
- Prediction of Hospital Mortality in Patients with ST Segment Elevation Myocardial Infarction: Evolution of Risk Measurement Techniques and Assessment of Their Effectiveness (Review).Sovremennye tekhnologii v meditsine · 2024Pooled it
- Prognostic impact of monocyte-to-lymphocyte ratio in coronary heart disease: a systematic review and meta-analysis.The Journal of international medical research · 2023Pooled it
- Association of inflammatory indicators with intensive care unit mortality in critically ill patients with coronary heart disease.Frontiers in immunology · 2023Trial
- Inflammatory burden index predicts arteriogenic erectile dysfunction: a mediation analysis involving the TyG index.Sexual medicine · 2026Article
- A nonlinear association between platelet-to-albumin ratio and one-year all-cause mortality in acute coronary syndrome patients.Annals of medicine · 2026Article
- Emerging Prognostic Risk Factors in Acute Coronary Syndromes: Beyond Traditional Risk Assessment.Journal of clinical medicine · 2026Review
- The Osaka Prognostic Score as a Novel Predictor of Contrast-Induced Nephropathy and In-Hospital Mortality in STEMI Patients Undergoing Primary Percutaneous Coronary Intervention.Acta Cardiologica Sinica · 2026Article
- Prognostic value of 9 immune-inflammatory markers for patients with dilated cardiomyopathy: A retrospective study.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Prognostic Value of Conventional and Modified Naples Scores for In-Hospital Mortality in Patients with Non-ST-Elevation Acute Coronary Syndrome.Medicina (Kaunas, Lithuania) · 2026Article
- Guselkumab treatment of psoriasis results in sustained reduction of systemic inflammatory biomarkers to week 48 in three phase III randomized controlled trials.Skin health and disease · 2026Article
- Limited Utility of Lymphocyte-Based Inflammatory Indices in Troponin-Negative Unstable Angina Pectoris.Journal of cardiovascular development and disease · 2026Article
- Association of cumulative systemic inflammation response index and all-cause mortality in adult with cardiovascular-kidney-metabolic syndrome stages 0-2: a prospective cohort study.BMC cardiovascular disorders · 2026Article
- The Role of Serum Biomarkers for the Differential Diagnosis and Prognostic Assessment of Myocardial Infarction with Non-Obstructive Coronary Arteries: A Narrative Review.Journal of clinical medicine · 2026Review
- Multidomain Biomarkers as Predictors of Cardiovascular Risk in Acute Coronary Syndrome: A Prospective Evaluation.International journal of molecular sciences · 2026Article
- Enhanced predictive value of post-treatment lymphocyte-based immunoinflammatory biomarkers for cancer therapy-related cardiac dysfunction in anthracycline-treated breast cancer patients.Cardio-oncology (London, England) · 2026Article
- Unsupervised Clustering of Routine Inflammatory Markers in Cardiogenic Shock Reveals Phenotypic Heterogeneity Without Prognostic Utility.Journal of personalized medicine · 2026Article
- Study of the prognostic value of the systemic immune-inflammation index combined with the triglyceride-glucose index in coronary heart disease: a retrospective study based on the MIMIC database.BMC cardiovascular disorders · 2026Article
- Inflammatory indices as independent predictors of in-hospital mortality in acute upper gastrointestinal bleeding.BMC gastroenterology · 2026Observational
50 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The aim of this study was to evaluate the prognostic values of five lymphocyte-based inflammatory indices (platelet-lymphocyte ratio [PLR], neutrophil-lymphocyte ratio [NLR], monocyte-lymphocyte ratio [MLR], systemic immune inflammation index [SII], and system inflammation response index [SIRI]) in patients with acute coronary syndrome (ACS). Methods: A total of 1,701 ACS patients who underwent percutaneous coronary intervention (PCI) were included in this study and followed up for major adverse cardiovascular events (MACE) including all-cause death, non-fatal ischemic stroke, and non-fatal myocardial infarction. The five indices were stratified by the optimal cutoff value for comparison. The association between each of the lymphocyte-based inflammatory indices and MACE was assessed by the Cox proportional hazards regression analysis. Results: During the median follow-up of 30 months, 107 (6.3%) MACE were identified. The multivariate COX analysis showed that all five indices were independent predictors of MACE, and SIRI seemingly performed best (Hazard ratio [HR]: 3.847; 95% confidence interval [CI]: [2.623-5.641]; Conclusion: Lymphocyte-based inflammatory indices were significantly and independently associated with MACE in ACS patients who underwent PCI. SIRI seemed to be better than the other four indices in predicting MACE, and the combination of SIRI with the GRACE risk score could predict MACE more accurately.
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