Evidence map›Paper›PMID 35591903›Full record

ArticleRheumatology advances in practice2022

Long-term use of glucocorticoids for polymyalgia rheumatica: follow-up of the PMR Cohort Study.

Sara Muller, Samantha L Hider, Balamrit Singh Sokhal, Sarah A Lawton, Toby Helliwell, Christian D Mallen

Open access · goldAbstract read
In one paragraph

Article in Rheumatology advances in practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Sara MullerPrimary Care Centre, Versus Arthritis, School of Medicine, Keele University, Keele.ORCID https://orcid.org/0000-0001-6645-5751
Samantha L HiderPrimary Care Centre, Versus Arthritis, School of Medicine, Keele University, Keele.ORCID https://orcid.org/0000-0002-9958-3909
Balamrit Singh SokhalSchool of Medicine.ORCID https://orcid.org/0000-0002-2315-0744
Sarah A LawtonKeele Clinical Trials Unit, School of Medicine, Keele University, Keele.
Toby HelliwellPrimary Care Centre, Versus Arthritis, School of Medicine, Keele University, Keele.
Christian D MallenPrimary Care Centre, Versus Arthritis, School of Medicine, Keele University, Keele.ORCID https://orcid.org/0000-0002-2677-1028
Midlands Partnership NHS Foundation Trust · GBArthritis UK · GBIndiana University School of MedicineKeele University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: PMR is a common inflammatory condition in older adults, characterized by bilateral hip and shoulder pain and stiffness. Reducing oral glucocorticoids, classically used for ≤2 years, are the mainstay of treatment. This study considers the factors early in the disease course that might be associated with prolonged treatment. Methods: Six hundred and fifty-two people with incident PMR were recruited from English general practices (2012-2014). Participants completed seven questionnaires over 2 years (used to allocate people to pain-stiffness trajectories) and a further long-term follow-up (LTFU) questionnaire a median of 5.16 years after diagnosis. Characteristics of those still taking and having ceased glucocorticoids were described and compared using Kruskal-Wallis and χ Results: Of the 197 people completing the LTFUQ questionnaire, 179 people reported ever having taken glucocorticoids. Of these, 40.1% were still on treatment, with a median (quartile 1, quartile 3) daily dose of 5 (1.5, 9)  mg. People still taking glucocorticoids were more likely to be older (72.5 Conclusions: PMR is not always a time-limited condition. Few patient characteristics are associated with prolonged treatment early in the disease course, but those who are older and who have sustained symptoms might be at greater risk. Although accurate prediction is not yet possible, clinicians should monitor people with PMR carefully to manage symptoms and reduce the cumulative glucocorticoid dose.

Indexed as

cohort studiesPMRprimary health care

Identifiers

PMID35591903
PMCPMC9113421
OpenAlexW4280534787

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.