Widespread interspecific phylogenetic tree incongruence between mosquito-borne and insect-specific flaviviruses at hotspots originally identified in Zika virus.

Michael W Gaunt, John H-O Pettersson, Goro Kuno, Bill Gaunt, Xavier de Lamballerie, Ernest A Gould

Open access · goldAbstract read

In one paragraph

Article in Virus evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

1.2field-weighted citation impact, top 22% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Michael W GauntDepartment of Infection Biology London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

John H-O PetterssonDepartment of Medical Biochemistry and Microbiology, Zoonosis Science Center, Uppsala University, 751 23 Uppsala, Sweden.

Goro Kuno1648 Collindale Dr., Fort Collins, CO 80525, USA Formerly, Centers for Disease Control, Fort Collins, CO 80521, USA.

Bill GauntAeon-Sys, MBCS 29 Kensington Road, Barnsley S75 2TU, UK.

Xavier de LamballerieUMR "Unité des Virus Emergents", Aix-Marseille Université-IRD 190-Inserm 1207-IHU Méditerranée Infection, Marseille, France.ORCID https://orcid.org/0000-0001-7895-2720

Ernest A GouldUMR "Unité des Virus Emergents", Aix-Marseille Université-IRD 190-Inserm 1207-IHU Méditerranée Infection, Marseille, France.

Inserm · FROsys Technology · GBUniversity of London · GBUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraspecies (homologous) phylogenetic incongruence, or 'tree conflict' between different loci within the same genome of mosquito-borne flaviviruses (MBFV), was first identified in dengue virus (DENV) and subsequently in Japanese encephalitis virus (JEV), St Louis encephalitis virus, and Zika virus (ZIKV). Recently, the first evidence of phylogenetic incongruence between interspecific members of the MBFV was reported in ZIKV and its close relative, Spondweni virus. Uniquely, these hybrid proteomes were derived from four incongruent trees involving an

Indexed as

flavivirusMosquito-borne virusesphylogenetic incongruencerecombinationRY-codingselection

Identifiers

PMID35591877

DOI10.1093/ve/veac027

PMCPMC9113262

OpenAlexW4285282602

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.