Evidence map›Paper›PMID 35591850›Full record

ArticleHepatic medicine : evidence and research2022

Prevalence of HIV and Its Co-Infection with Hepatitis B/C Virus Among Chronic Liver Disease Patients in Ethiopia.

Yayehyirad Tassachew, Tamrat Abebe, Yeshambel Belyhun, Tezazu Teffera, Abate Bane Shewaye, Hailemichael Desalegn, Henok Andualem, Abiy Kinfu, Andargachew Mulu, Adane Mihret and 2 more

Open access · goldAbstract read
In one paragraph

Article in Hepatic medicine : evidence and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Yayehyirad TassachewDepartment of Microbiology, Immunology, and Parasitology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0002-9261-2850
Tamrat AbebeDepartment of Microbiology, Immunology, and Parasitology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Yeshambel BelyhunSchool of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Tezazu TefferaDepartment of Surgery, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Abate Bane ShewayeDepartment of Internal Medicine, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Hailemichael DesalegnDepartment of Internal Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.ORCID 0000-0003-2042-5797
Henok AndualemDepartment of Medical Laboratory Science, College of Medicine and Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID 0000-0001-6883-9548
Abiy KinfuEthiopian National Blood Bank Service, Addis Ababa, Ethiopia.ORCID 0000-0001-6489-9180
Andargachew MuluArmauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia.
Adane MihretDepartment of Microbiology, Immunology, and Parasitology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0003-3183-4772
Rawleigh HoweArmauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia.
Abraham AseffaArmauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia.ORCID 0000-0002-8028-1150
Armauer Hansen Research Institute · ETAddis Ababa University · ETHawassa University · ETDebre Tabor University · ETSt. Paul's Hospital Millennium Medical College · ETUniversity of Gondar · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The efficient use of antiretroviral drugs has significantly reduced AIDS-related morbidities and mortalities; however, mortality due to non-AIDS-related end-stage liver diseases is escalating in those living with HIV. Objective: The study was designed to determine the prevalence of HIV and its co-infection with HBV and HCV among chronic liver disease (CLD) patients in Ethiopia. Methods: Three hundred and forty-five CLD patients were included in this study in two groups: Hepatocellular carcinoma (HCC) (n=128) and non-HCC (n=217) patients. The non-HCC group comprised patients with advanced liver disease (n=98) and chronic hepatitis (n=119). Enzyme immunoassays were used to determine HBV and HCV infection markers. In addition, a serial rapid HIV testing algorithm was employed to screen HIV infection. Results: Regardless of the stage of liver disease, the overall frequency of HIV was 4.3% (15/345), with a 2% (7/345) and 0.3% (1/345) of HIV/HBV and HIV/HCV co-infection rate. Of all HIV-infected patients (n=15), 46.7% (7/15) and 6.7% (1/15) were co-infected with HBV (HBsAg Conclusion: The frequency of HIV and its co-infections with HBV/HCV exhibited an increasing pattern with the severity of the liver disease. Thus, screening all HIV-positive patients for HBV and HCV infection and all CLD patients for HIV infection and taking necessary preventive measures would be an essential strategy to prevent the progression of CLD and death related to liver disease in people living with HIV.

Indexed as

HBVHCCHCVHIVnon-AIDS liver diseases

Identifiers

PMID35591850
PMCPMC9113656
OpenAlexW4280639386

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.