Evidence map›Paper›PMID 35591811›Full record

Trial reportPhysiological reports2022

Cardiovascular responses to high-intensity stair climbing in individuals with coronary artery disease.

Sydney E Valentino, Emily C Dunford, Jonathan Dubberley, Eva M Lonn, Martin J Gibala, Stuart M Phillips, Maureen J MacDonald

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03235674 (A Feasible High Intensity Interval Exercise Training Intervention in Phase II Cardiac Rehabilitation), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03235674 nacompletednot on this map

A Feasible High Intensity Interval Exercise Training Intervention in Phase II Cardiac Rehabilitation

TypeinterventionalSponsorMcMaster UniversityRan2018 to 2019Enrolled20ConditionsEndothelial DysfunctionArmsHigh-intensity stair climbing exercise
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sydney E ValentinoDepartment of Kinesiology, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0003-2280-8505
Emily C DunfordDepartment of Kinesiology, McMaster University, Hamilton, Ontario, Canada.
Jonathan DubberleyHamilton Health Sciences, Hamilton, Ontario, Canada.
Eva M LonnHamilton Health Sciences, Hamilton, Ontario, Canada.ORCID 0000-0002-0156-6730
Martin J GibalaDepartment of Kinesiology, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-5287-0014
Stuart M PhillipsDepartment of Kinesiology, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-1956-4098
Maureen J MacDonaldDepartment of Kinesiology, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-9851-3610
McMaster University · CAHamilton Health Sciences · CAPopulation Health Research Institute · CA

Funding

CIHR
6 · The paper itself

Abstract

Exercise-based cardiac rehabilitation leads to improvements in cardiovascular function in individuals with coronary artery disease. The cardiac effects of coronary artery disease (CAD) can be quantified using clinical echocardiographic measures, such as ejection fraction (EF). Measures of cardiovascular function typically only used in research settings can provide additional information and maybe more sensitive indices to assess changes after exercise-based cardiac rehabilitation. These additional measures include endothelial function (measured by flow-mediated dilation), left ventricular twist, myocardial performance index, and global longitudinal strain. To investigate the cardiovascular response to 12 week of either traditional moderate-intensity (TRAD) or stair climbing-based high-intensity interval (STAIR) exercise-based cardiac rehabilitation using both clinical and additional measures of cardiovascular function in individuals with CAD. Measurements were made at baseline (BL) and after supervised (4wk) and unsupervised (12 week) of training. This study was registered as a clinical trial at clinicaltrials.gov (NCT03235674). Participants were randomized into either TRAD (n = 9, 8M/1F) and STAIR (n = 9, 8M/1F). There was a training-associated increase in one component of left ventricular twist: Cardiac apical rotation (TRAD: BL: 5.6 ± 3.3º, 4 week: 8.0 ± 3.9º, 12 week: 6.2 ± 5.1º and STAIR: BL: 5.1 ± 3.6º, 4 week: 7.4 ± 3.9º, 12 week: 7.8 ± 2.8º, p (time) = 0.03, η

Indexed as

Cardiac RehabilitationCoronary Artery DiseaseHigh-Intensity Interval TrainingStair ClimbingExercise TherapyHumanscardiac functioncardiac rehabilitationflow-mediated dilationHIITstair climbing

Identifiers

PMID35591811
PMCPMC9120873
OpenAlexW4280636205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.