ArticleJournal of cachexia, sarcopenia and muscle2022
Lifetime body mass index and grip strength at age 46 years: the 1970 British Cohort Study.
Article in Journal of cachexia, sarcopenia and muscle, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Effect of a 16-Week Exercise Program After Bariatric Surgery on Sarcopenia Parameters Based on FNIH, EWGSOP2, and EASO/ESPEN Criteria: the Results of the EXPOBAR Randomized Trial Program.Obesity surgery · 2025Trial
- The impact of bariatric surgery and exercise on systemic immune inflammation index in patients with sarcopenia obesity.Scientific reports · 2025Trial
- Application of the SF-BARI Score for Evaluating long-term Metabolic and Clinical Outcomes after Bariatric Surgery.Obesity surgery · 2026Article
- Longitudinal association between body mass index and handgrip strength in community-dwelling older adults: a population-based nationwide cohort study.BMC geriatrics · 2025Article
- Grip strength: are some adiposity phenotypes more detrimental than others? A Mendelian randomization study.Obesity (Silver Spring, Md.) · 2025Observational
- Association between hand grip strength and bone mineral density in US adolescents aged 12-19 years: a cross-sectional study.European journal of pediatrics · 2025Article
- The relationship between age related changes in strength and fitness with body size, shape and composition.Scientific reports · 2025Article
- The Different Body Mass Index Does Not Impact Physical Health in Older Adults without Sedentary Behavior: A Cross-Sectional Study.Current aging science · 2025Article
- Prevalence and Risk Factors for Hand-Grip-Determined Dynapenia in the Korean Population: A Cross-Sectional Study.Sports (Basel, Switzerland) · 2024Article
- Predictors of Hand Grip Strength in Adults Without Sarcopenia: Data From the NHANES, 2013-2014.Current developments in nutrition · 2024Article
- The association between weight-adjusted-waist index and muscle strength in adults: a population-based study.Frontiers in public health · 2024Article
- Associations between tri-ponderal mass index, body mass index, and high blood pressure among children and adolescents: a cross-sectional study.Scientific reports · 2023Article
- Chronic inflammation does not mediate the effect of adiposity on grip strength: results from a multivariable Mendelian randomization study.Scientific reports · 2023Article
- Handgrip Strength and Muscle Quality: Results from the National Health and Nutrition Examination Survey Database.Journal of clinical medicine · 2023Article
- Cross-sectional and longitudinal associations between body flexibility and sarcopenia.Journal of cachexia, sarcopenia and muscle · 2023Article
- Lifetime body mass index and grip strength at age 46 years: the 1970 British Cohort Study.Journal of cachexia, sarcopenia and muscle · 2022Article
- Adiposity and grip strength: a Mendelian randomisation study in UK Biobank.BMC medicine · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundOngoing rises in obesity prevalence have prompted growing concerns about potential increases in the burden of age-related musculoskeletal conditions including sarcopenia and sarcopenic obesity. This is of particular concern for future generations of older adults who have lived more of their lives in an obesogenic environment than current generations of older adults. We aimed to study longitudinal associations between body mass index (BMI) and grip strength in midlife using data from a large population-based sample, the 1970 British Cohort Study (BCS70).
methodsBCS70 participants with valid measures of maximum grip strength at age 46 years were included in analyses [3671 males (49%) and 3876 females (51%)]. Using sex-specific linear regression models, we examined associations of (i) BMI at ages 10, 16, 30, and 46 years; (ii) body fat percentage (BF%) and waist-hip ratio at age 46 years; (iii) BMI gains between 10-16, 16-30, and 30-46; and (iv) age at onset of obesity, with grip strength.
resultsAt age 46 years, mean (standard deviation) grip strength was 48.10 kg (8.98) in males and 29.61 kg (5.81) in females. Higher BMI at all ages was associated with stronger grip, and the scale of associations was greater in males than females from age 16 onwards (P
conclusionsHigher BMI from childhood onwards is associated with stronger grip at age 46 years. This suggests that, at this age, anabolic effects of fat on muscle are outweighing the catabolic effects thought to lead to the manifestation of sarcopenic obesity later in life, especially among men. Midlife may be an optimal time to intervene to prevent sarcopenic obesity.
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