ArticleMaterials (Basel, Switzerland)2022
Titanium Surface Modification for Implantable Medical Devices with Anti-Bacterial Adhesion Properties.
Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The trial behind it
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Who cites it
22 citing papers in PubMed, 31 citations in OpenAlex.
- Bioengineered titanium implants functionalized with aptamer-valproic acid conjugates orchestrate macrophage programming and mesenchymal stem cell homing for improved osseointegration.Bioactive materials · 2026Article
- The Standardization and Comparability Gap in Evaluating Antibacterial Surfaces for Load-Bearing Orthopedic Implants: A Critical Review.Bioengineering (Basel, Switzerland) · 2026Review
- Inhibiting biofilm growth on ammonium salt-functionalized or fluorinated voice prostheses silicone.Applied microbiology and biotechnology · 2026Article
- Surface Characterization and Antimicrobial Capability Evaluation of Medical-Grade Titanium Modified by Facile Immersion in the Solution of Novel Catechol-Terminated Compounds Having Cationic Quaternary Ammonium Functionality with Different Alkyl Chain Lengths.Journal of functional biomaterials · 2026Article
- Resistance mechanisms of bacterial biofilms on orthopedic implants and research progress on novel anti-biofilm coatings.Frontiers in bioengineering and biotechnology · 2026Review
- Bioengineering methods for tailoring treatment of Osteomyelitis: Advancing strategies and application.Materials today. Bio · 2025Review
- Bacterial Biofilms-A Threat to Biliary Stents, Understanding Their Formation, Clinical Consequences and Management.Medicina (Kaunas, Lithuania) · 2025Review
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- Article
- Using the Aqueous Phase Produced from Hydrothermal Carbonization Process of Brown Seaweed to Improve the Growth ofPlants (Basel, Switzerland) · 2023Article
- Modulation of Cell Response through the Covalent Binding of Fibronectin to Titanium Substrates.Journal of functional biomaterials · 2023Article
- Epigenetic Differences Arise in Endothelial Cells Responding to Cobalt-Chromium.Journal of functional biomaterials · 2023Article
- Biofunctionalization of Porous Titanium Oxide through Amino Acid Coupling for Biomaterial Design.Materials (Basel, Switzerland) · 2023Article
- Titanium surfaces with biomimetic topography and copper incorporation to modulate behaviors of stem cells and oral bacteria.Frontiers in bioengineering and biotechnology · 2023Article
- Surface Modification of Additively Fabricated Titanium-Based Implants by Means of Bioactive Micro-Arc Oxidation Coatings for Bone Replacement.Journal of functional biomaterials · 2022Article
- Why Is Tantalum Less Susceptible to Bacterial Infection?Journal of functional biomaterials · 2022Article
- Chitosan/POSS Hybrid Hydrogels for Bone Tissue Engineering.Materials (Basel, Switzerland) · 2022Article
- Remote Eradication of Bacteria on Orthopedic Implants via Delayed Delivery of Polycaprolactone Stabilized Polyvinylpyrrolidone Iodine.Journal of functional biomaterials · 2022Article
- Modulation of Osteogenesis and Angiogenesis Activities Based on Ionic Release from Zn-Mg Alloys.Materials (Basel, Switzerland) · 2022Article
- Design and Development of Fluorinated and Biocide-Free Sol-Gel Based Hybrid Functional Coatings for Anti-Biofouling/Foul-Release Activity.Gels (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pure titanium and titanium alloys are widely used in dentistry and orthopedics. However, despite their outstanding mechanical and biological properties, implant failure mainly due to post-operative infection still remains a significant concern. The possibility to develop inherent antibacterial medical devices was here investigated by covalently inserting bioactive ammonium salts onto the surface of titanium metal substrates. Titanium discs have been functionalized with quaternary ammonium salts (QASs) and with oleic acid (OA), affording the Ti-AEMAC Ti-GTMAC, Ti-AUTEAB, and Ti-OA samples, which were characterized by ATR-FTIR and SEM-EDX analyses and investigated for the roughness and hydrophilic behavior. The chemical modifications were shown to deeply affect the surface properties of the metal substrates and, as a consequence, their bio-interaction. The bacterial adhesion tests against the Gram-negative
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.