ReviewMaterials (Basel, Switzerland)2022
Diabetes Mellitus and Dental Implants: A Systematic Review and Meta-Analysis.
Review in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Clinical and radiographic outcomes of mini-implant-retained maxillary and mandibular overdentures: a systematic review and meta-analysis.Clinical oral investigations · 2025Pooled it
- Dental implant failure and retrieval techniques; a scoping review.Frontiers in oral health · 2025Pooled it
- Clinical outcomes of zirconia implants: a systematic review and meta-analysis.Clinical oral investigations · 2023Pooled it
- Angiogenic and Regenerative Potential of Plasma-Based and Plasma-Free Platelet Concentrates Obtained via Different Fractionation and Activation Methods.Bioengineering (Basel, Switzerland) · 2026Article
- Article
- Enhancing dental implant outcomes in type 2 diabetes: Addressing inflammation and risk factors.World journal of diabetes · 2026Article
- The Prevalence of Early Implant Failure and Associated Risk Factors: A Retrospective Study.Journal of clinical and experimental dentistry · 2026Review
- Article
- Analysis of inflammatory response and its factors after dental implant surgery in patients with type 2 diabetes.World journal of diabetes · 2025Article
- Medication-Related Osteonecrosis of the Jaws in Patients on Antiresorptive Medication With Dental Implants. A Scoping Review.Clinical oral implants research · 2025Article
- Clinical evaluation of tapered-straight-tapered dental implants: a retrospective analysis.Journal of periodontal & implant science · 2025Article
- Connection between oral health and chronic diseases.MedComm · 2025Review
- Review
- An Umbrella Review of the Association Between Periodontal Disease and Diabetes Mellitus.Healthcare (Basel, Switzerland) · 2024Review
- Correlation between marginal bone loss around dental implants and various systemic diseases: a cross-sectional study.International journal of implant dentistry · 2024Article
- Effect of osteopenia and osteoporosis on failure of first and second dental implants: a retrospective observational study.International journal of implant dentistry · 2024Observational
- Clinical Outcomes of Pterygoid and Maxillary Tuberosity Implants: A Systematic Review.Journal of clinical medicine · 2024Review
- Clinical-statistical study on oral rehabilitation methods using dental implants.Medicine and pharmacy reports · 2024Article
- Could Dental Material Reuse Play a Significant Role in Preservation of Raw Materials, Water, Energy, and Costs? Microbiological Analysis of New versus Reused Healing Abutments: An In Vitro Study.Bioengineering (Basel, Switzerland) · 2024Article
- Clinical Outcomes of Maxillary Sinus Floor Perforation by Dental Implants and Sinus Membrane Perforation during Sinus Augmentation: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present review aimed to evaluate the impact of diabetes mellitus on dental implant failure rates and marginal bone loss (MBL). An electronic search was undertaken in three databases, plus a manual search of journals. Meta-analyses were performed as well as meta-regressions in order to verify how the odds ratio (OR) and MBL were associated with follow-up time. The review included 89 publications. Altogether, there were 5510 and 62,780 implants placed in diabetic and non-diabetic patients, respectively. Pairwise meta-analysis showed that implants in diabetic patients had a higher failure risk in comparison to non-diabetic patients (OR 1.777, p < 0.001). Implant failures were more likely to occur in type 1 diabetes patients than in type 2 (OR 4.477, p = 0.032). The difference in implant failure between the groups was statistically significant in the maxilla but not in the mandible. The MBL mean difference (MD) between the groups was 0.776 mm (p = 0.027), with an estimated increase of 0.032 mm in the MBL MD between groups for every additional month of follow-up (p < 0.001). There was an estimated decrease of 0.007 in OR for every additional month of follow-up (p = 0.048). In conclusion, implants in diabetic patients showed a 77.7% higher risk of failure than in non-diabetic patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.