Evidence map›Paper›PMID 35591484›Full record

ReviewMaterials (Basel, Switzerland)2022

Titanium Dental Implants: An Overview of Applied Nanobiotechnology to Improve Biocompatibility and Prevent Infections.

Rayane C S Silva, Almerinda Agrelli, Audrey N Andrade, Carina L Mendes-Marques, Isabel R S Arruda, Luzia R L Santos, Niedja F Vasconcelos, Giovanna Machado

Open access · goldAbstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Rapid mineralization of hydrothermally induced TiOJournal of materials science. Materials in medicine · 2026
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  20. Sustained release of Sr and Ca from a micronanotopographic titanium surface improves osteoblast function.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rayane C S SilvaCentro de Tecnologias Estratégicas do Nordeste-Cetene, Av. Prof. Luiz Freire, 01, Cidade Universitária, Recife CEP 50740-545, PE, Brazil.ORCID 0000-0002-4765-7283
Almerinda AgrelliCentro de Tecnologias Estratégicas do Nordeste-Cetene, Av. Prof. Luiz Freire, 01, Cidade Universitária, Recife CEP 50740-545, PE, Brazil.ORCID 0000-0002-9908-742X
Audrey N AndradeCentro de Tecnologias Estratégicas do Nordeste-Cetene, Av. Prof. Luiz Freire, 01, Cidade Universitária, Recife CEP 50740-545, PE, Brazil.
Carina L Mendes-MarquesCentro de Tecnologias Estratégicas do Nordeste-Cetene, Av. Prof. Luiz Freire, 01, Cidade Universitária, Recife CEP 50740-545, PE, Brazil.ORCID 0000-0002-3111-7063
Isabel R S ArrudaCentro de Tecnologias Estratégicas do Nordeste-Cetene, Av. Prof. Luiz Freire, 01, Cidade Universitária, Recife CEP 50740-545, PE, Brazil.ORCID 0000-0001-9783-0534
Luzia R L SantosCentro de Tecnologias Estratégicas do Nordeste-Cetene, Av. Prof. Luiz Freire, 01, Cidade Universitária, Recife CEP 50740-545, PE, Brazil.ORCID 0000-0002-2435-3957
Niedja F VasconcelosCentro de Tecnologias Estratégicas do Nordeste-Cetene, Av. Prof. Luiz Freire, 01, Cidade Universitária, Recife CEP 50740-545, PE, Brazil.ORCID 0000-0002-2440-0039
Giovanna MachadoCentro de Tecnologias Estratégicas do Nordeste-Cetene, Av. Prof. Luiz Freire, 01, Cidade Universitária, Recife CEP 50740-545, PE, Brazil.
Centro de Tecnologias Estratégicas do Nordeste · BR

Funding

Fundação de Amparo a Ciência e Tecnologia do Estado de Pernambuco APQ-0516-9.25/19National Council for Scientific and Technological Development 309910/2021-8National Council for Scientific and Technological Development 442477/2019-8
6 · The paper itself

Abstract

This review addresses the different aspects of the use of titanium and its alloys in the production of dental implants, the most common causes of implant failures and the development of improved surfaces capable of stimulating osseointegration and guaranteeing the long-term success of dental implants. Titanium is the main material for the development of dental implants; despite this, different surface modifications are studied aiming to improve the osseointegration process. Nanoscale modifications and the bioactivation of surfaces with biological molecules can promote faster healing when compared to smooth surfaces. Recent studies have also pointed out that gradual changes in the implant, based on the microenvironment of insertion, are factors that may improve the integration of the implant with soft and bone tissues, preventing infections and osseointegration failures. In this context, the understanding that nanobiotechnological surface modifications in titanium dental implants improve the osseointegration process arouses interest in the development of new strategies, which is a highly relevant factor in the production of improved dental materials.

Indexed as

biofilmsbone–implant interfacecoatingnanotechnologyosseointegrationprostheses and implantssurface modifications

Identifiers

PMID35591484
PMCPMC9104688
OpenAlexW4225015834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.