Evidence map›Paper›PMID 35590912›Full record

ReviewSensors (Basel, Switzerland)2022

Colorimetric Paper-Based Sensors against Cancer Biomarkers.

Mariana C C G Carneiro, Ligia R Rodrigues, Felismina T C Moreira, Maria Goreti F Sales

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Surface Engineering of MXene and Functional Fullerenols for Cancer Biomarker 'eIFLangmuir : the ACS journal of surfaces and colloids · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mariana C C G CarneiroBioMark@ISEP, School of Engineering, Polytechnic Institute, 4249-015 Porto, Portugal.
Ligia R RodriguesCentre of Biological Engineering, Minho University (CEB), 4710-057 Braga, Portugal.ORCID 0000-0001-9265-0630
Felismina T C MoreiraBioMark@ISEP, School of Engineering, Polytechnic Institute, 4249-015 Porto, Portugal.ORCID 0000-0003-4237-8952
Maria Goreti F SalesCentre of Biological Engineering, Minho University (CEB), 4710-057 Braga, Portugal.ORCID 0000-0001-9936-7336

Funding

Fundação para a Ciência e Tecnologia SFRH/BD/131959/2017.
6 · The paper itself

Abstract

Cancer is a major cause of mortality and morbidity worldwide. Detection and quantification of cancer biomarkers plays a critical role in cancer early diagnosis, screening, and treatment. Clinicians, particularly in developing countries, deal with high costs and limited resources for diagnostic systems. Using low-cost substrates to develop sensor devices could be very helpful. The interest in paper-based sensors with colorimetric detection increased exponentially in the last decade as they meet the criteria for point-of-care (PoC) devices. Cellulose and different nanomaterials have been used as substrate and colorimetric probes, respectively, for these types of devices in their different designs as spot tests, lateral-flow assays, dipsticks, and microfluidic paper-based devices (μPADs), offering low-cost and disposable devices. However, the main challenge with these devices is their low sensitivity and lack of efficiency in performing quantitative measurements. This review includes an overview of the use of paper for the development of sensing devices focusing on colorimetric detection and their application to cancer biomarkers. We highlight recent works reporting the use of paper in the development of colorimetric sensors for cancer biomarkers, such as proteins, nucleic acids, and others. Finally, we discuss the main advantages of these types of devices and highlight their major pitfalls.

Indexed as

Microfluidic Analytical TechniquesNeoplasmsBiomarkersBiomarkers, TumorColorimetryLab-On-A-Chip DevicesPaperPoint-of-Care SystemsBiomarkersBiomarkers, Tumorcancer diagnosiscolorimetric detectionpaper-based devices

Identifiers

PMID35590912
PMCPMC9102172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.