Evidence map›Paper›PMID 35590420›Full record

ArticleCell & bioscience2022

Ginkgolic acid and anacardic acid are reversible inhibitors of SARS-CoV-2 3-chymotrypsin-like protease.

Dongsheng Li, Gangan Yan, Wenwen Zhou, Shuyi Si, Xiaoping Liu, Jing Zhang, Yan Li, Yunyu Chen

Open access · goldAbstract readLetter
In one paragraph

Article in Cell & bioscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dongsheng Li *Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Gangan Yan *Institute for Drug Screening and Evaluation, Wannan Medical College, Wuhu, 241002, China.
Wenwen ZhouInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Shuyi SiInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Xiaoping LiuInstitute for Drug Screening and Evaluation, Wannan Medical College, Wuhu, 241002, China.
Jing ZhangInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. jingjing-506@hotmail.com.ORCID http://orcid.org/0000-0003-2299-1979
Yan LiInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. 13391513480@163.com.
Yunyu ChenInstitute for Drug Screening and Evaluation, Wannan Medical College, Wuhu, 241002, China. chenyunyu1984@163.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNWannan Medical College · CN

Funding

CAMS Innovation Fund for Medical Sciences 2021-I2M-1-054Key Technologies Research and Development Program of Anhui Province 202004a07020041National Natural Science Foundation of China 81370087National Natural Science Foundation of China 81703546National Natural Science Foundation of China 81773784Natural Science Foundation of Anhui Province 1808085QH265University Natural Science Research Project of Anhui Province KJ2019ZD30University Natural Science Research Project of Anhui Province KJ2021A0839University Natural Science Research Project of Anhui Province YJS20210549Young Talent Project of Wannan Medical College wyqnyx202104
6 · The paper itself

Abstract

Because of the emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in different regions of the world, the battle with infectious coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has been seesawing. Therefore, the identification of antiviral drugs is of particular importance. In order to rapidly identify inhibitors for SARS-CoV-2 3-chymotrypsin-like protease (3CL

Indexed as

3CL protease inhibitorAnacardic acidGinkgolic acidMixed-inhibition mannerNon-covalentReversibleSARS-CoV-2

Identifiers

PMID35590420
PMCPMC9118179
OpenAlexW4280537982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.