Evidence map›Paper›PMID 35590395›Full record

ArticleTrials2022

The Symptom Monitoring with Feedback Trial (SWIFT): protocol for a registry-based cluster randomised controlled trial in haemodialysis.

Lavern Greenham, Paul N Bennett, Kathryn Dansie, Andrea K Viecelli, Shilpanjali Jesudason, Rebecca Mister, Brendan Smyth, Portia Westall, Samuel Herzog, Chris Brown and 7 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06257134 (Impact on Quality of Life of Symptoms Routine E-monitoring Among Dialysis Patients, With Results Notification to Teams. A Cluster Randomised Controlled Trial Nested in a National Registry F-SWIFT), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06257134 narecruitingnot on this mapstarted 2026, after this paper: background citation

Impact on Quality of Life of Symptoms Routine E-monitoring Among Dialysis Patients, With Results Notification to Teams. A Cluster Randomised Controlled Trial Nested in a National Registry F-SWIFT (French Symptom Monitoring WIth Feedback Trial)

TypeinterventionalSponsorCentral Hospital, Nancy, FranceRan2026 to 2026Enrolled2,293ConditionsEnd Stage Renal DiseaseArmsNo systematic monitoring of symptoms, Systematic monitoring of symptoms
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Interventions for fatigue in people with kidney failure requiring dialysis.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Health-related quality of life and symptom burden in patients on haemodialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  10. Advances in Human-Centered Care to Address Contemporary Unmet Needs in Chronic Dialysis.International journal of nephrology and renovascular disease · 2024
    Review
  11. Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 5 countries.

Lavern GreenhamAustralia and New Zealand Dialysis and Transplant Registry, Adelaide, SA, Australia.
Paul N BennettSatellite Healthcare, San Jose, CA, USA.
Kathryn DansieAustralia and New Zealand Dialysis and Transplant Registry, Adelaide, SA, Australia.
Andrea K ViecelliPrincess Alexandra Hospital, Woolloongabba, QLD, Australia.
Shilpanjali JesudasonCentral Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital, Adelaide, SA, Australia.
Rebecca MisterNHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW, Australia.
Brendan SmythNHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW, Australia.
Portia WestallNHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW, Australia.
Samuel HerzogNHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW, Australia.
Chris BrownNHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW, Australia.
William HandkeConsumer Representative, Canberra, ACT, Australia.
Suetonia C PalmerUniversity of Otago, Canterbury, Christchurch, New Zealand.
Fergus J CaskeyUniversity of Bristol, Bristol, UK.
Cecile CouchoudRenal Epidemiology and Information Network (REIN), Agence de la Biomédecine, Saint-Denis, Paris, France.
John SimesNHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW, Australia.
Stephen P McDonaldAustralia and New Zealand Dialysis and Transplant Registry, Adelaide, SA, Australia.
Rachael L MortonNHMRC Clinical Trials Centre, University of Sydney, Camperdown, NSW, Australia. rachael.morton@sydney.edu.au.
National Health and Medical Research Council · AUAustralia and New Zealand Dialysis and Transplant Registry · AUThe University of Adelaide · AUAgence de la Biomédecine · FRPrincess Alexandra Hospital · AUSt George Hospital · AUThe University of Sydney · AUUniversity of Bristol · GBUniversity of Otago · NZUniversity of South Australia · AU

Funding

National Health and Medical Research Council #1159051
6 · The paper itself

Abstract

backgroundKidney failure prevalence is increasing worldwide. Haemodialysis, peritoneal dialysis or kidney transplantation are undertaken to extend life with kidney failure. People receiving haemodialysis commonly experience fatigue, pain, nausea, cramping, itching, sleeping difficulties, anxiety and depression. This symptom burden contributes to poor health-related quality of life (QOL) and is a major reason for treatment withdrawal and death. The Symptom monitoring WIth Feedback Trial (SWIFT) will test the hypothesis that regular symptom monitoring with feedback to people receiving haemodialysis and their treating clinical team can improve QOL.

methodsWe are conducting an Australia and New Zealand Dialysis and Transplant (ANZDATA) registry-based cluster randomised controlled trial to determine the clinical- and cost-effectiveness at 12 months, of 3-monthly symptom monitoring using the Integrated Palliative Outcome Scale-Renal (IPOS-Renal) survey with clinician feedback, compared with usual care among adults treated with haemodialysis. Participants complete symptom scoring using a tablet, which are provided to participants and to clinicians. The trial aims to recruit 143 satellite haemodialysis centres, (up to 2400 participants). The primary outcome is change in health-related QOL, as measured by EuroQol 5-Dimension, 5-Level (EQ-5D-5L) instrument. Secondary outcomes include overall survival, symptom severity (including haemodialysis-associated fatigue), healthcare utilisation and cost-effectiveness. DISCUSSION: SWIFT is the first registry-based trial in the Australian haemodialysis population to investigate whether regular symptom monitoring with feedback to participants and clinicians improves QOL. SWIFT is embedded in the ANZDATA Registry facilitating pragmatic recruitment from public and private dialysis clinics, throughout Australia. SWIFT will inform future collection, storage and reporting of patient-reported outcome measures (PROMs) within a clinical quality registry. As the first trial to rigorously estimate the efficacy and cost-effectiveness of routine PROMs collection and reporting in haemodialysis units, SWIFT will provide invaluable information to health services, clinicians and researchers working to improve the lives of those with kidney failure.

trial registrationAustralian New Zealand Clinical Trials Registry ACTRN12620001061921 . Registered on 16 October 2020.

Indexed as

Renal DialysisRenal InsufficiencyAdultAustraliaFeedbackHumansPatient Reported Outcome MeasuresPragmatic Clinical Trials as TopicQuality of LifeRandomized Controlled Trials as TopicRegistriesChronic kidney diseaseCluster and randomised controlled trialHaemodialysisKidney replacement therapyPatient-reported outcomesQuality of lifeRegistryRenal dialysis

Identifiers

PMID35590395
PMCPMC9118566
OpenAlexW4280618149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.