SynthesisJournal of cardiothoracic surgery2022
Review of outcomes of delayed chest closure following lung transplantation: a meta-analysis.
Synthesis in Journal of cardiothoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Reassessing delayed chest closure in lung transplantation: Outcomes from a propensity score-matched cohort.JTCVS open · 2026Article
- Article
- Predicting Primary Graft Dysfunction in Systemic Sclerosis Lung Transplantation Using Machine-Learning and CT Features.Clinical transplantation · 2025Article
- Outcomes of lung transplantation for scleroderma versus other indications: Insigts from a single center.JHLT open · 2025Article
- CT-Based Lung Size Matching in Delayed Chest Closure for Systemic Sclerosis Lung Transplantation.Clinical transplantation · 2024Article
- Long-term survival and clinical outcomes of delayed chest closure following lung transplantation.Surgery today · 2024Article
- Small recipient chest cavity from fibrotic lung disease in lung transplantation: Physiology matters.JHLT open · 2024Review
- Size-matching in lung transplantation by computed tomography for end-stage interstitial disease: a retrospective analysis.Journal of thoracic disease · 2024Article
- Delayed rib plating and lung herniation repair in a traumatic chest injury after thoracotomy: A case report.International journal of surgery case reports · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe clinical outcomes of delayed chest closure (DCC) compared with primary chest closure (PCC) following lung transplantation, including perioperative outcomes and long-term survival, remained controversial. This was the first systematic review and meta-analysis aimed to identify the short- and long-term outcomes of DCC following lung transplantation.
methodsWe comprehensively searched electronic literature from 4 databases up to April 1st, 2022. Dichotomous data and continuous data were pooled with odds ratio and weighted mean difference, respectively. The quality of included studies was assessed with the Newcastle-Ottawa Scale.
resultsTen studies were included in the systematic review and 4 studies were included in the meta-analysis. Pooled analysis showed that DCC was associated with an increased risk of surgical site infection, prolonged hospital stays, and higher risk of primary graft dysfunction compared to PCC. The 30 day and 5 year survival were higher in PCC cohort compared with DCC cohort while differences in survival at 6 months was insignificant.
conclusionOur findings do not support the aggressive application of DCC. DCC should be cautiously applied since its association with worse perioperative outcomes and higher mortality. But it remains the life-saving steps under dangerous circumstances.
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Registered trials
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