Evidence map›Paper›PMID 35590212›Full record

ArticleMed (New York, N.Y.)2022

Cell-free plasma RNA signatures as a surrogate biomarker of pregnancy health.

Yalda Afshar, S Ananth Karumanchi

Abstract readComment
PubMed Publisher
In one paragraph

Article in Med (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Yalda AfsharDepartment of Obstetrics and Gynecology, University of California at Los Angeles, Los Angeles, USA. Electronic address: yafshar@mednet.ucla.edu.
S Ananth KarumanchiDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, USA. Electronic address: sananth.karumanchi@csmc.edu.
Cedars-Sinai Medical Center · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular diagnostics based on sequencing of plasma cell-free DNA has transformed obstetric care by accurately diagnosing fetal aneuploidy in early pregnancy. Rasmussen et al. now report plasma cell-free RNA profiling that could transform obstetrics by providing comprehensive molecular monitoring of pregnancy progression for both healthy and complicated pregnancies such as preeclampsia.

Indexed as

Cell-Free Nucleic AcidsPre-EclampsiaAneuploidyBiomarkersFemaleHumansPregnancyRNABiomarkersCell-Free Nucleic AcidsRNA

Identifiers

PMID35590212
OpenAlexW4211127292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.