Evidence map›Paper›PMID 35590116›Full record

ArticleAnnals of surgical oncology2022

Endometrioid Borderline Ovarian Tumor: Clinical Characteristics, Prognosis, and Managements.

Giulio Ricotta, Amandine Maulard, Massimo Candiani, Stephanie Scherrier, Catherine Genestie, Patricia Pautier, Alexandra Leary, Cyrus Chargari, Giorgia Mangili, Philippe Morice and 1 more

Abstract read
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In one paragraph

Article in Annals of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. The Ultrasonography Characteristics of Borderline Ovarian Tumor Subtypes.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Giulio RicottaDepartment of Gynaecologic Surgery, Gustave-Roussy, Villejuif, France.
Amandine MaulardDepartment of Gynaecologic Surgery, Gustave-Roussy, Villejuif, France.
Massimo CandianiIRCCS San Raffaele Hospital, Vita-Salute University, Milan, Italy.
Stephanie ScherrierDepartment of Gynaecologic Surgery, Gustave-Roussy, Villejuif, France.
Catherine GenestieDepartment of Pathology, Gustave-Roussy, Villejuif, France.
Patricia PautierDepartment of Medical Oncology, Gustave-Roussy, Villejuif, France.
Alexandra LearyDepartment of Medical Oncology, Gustave-Roussy, Villejuif, France.
Cyrus ChargariDepartment of Radiation Oncology, Gustave-Roussy, Villejuif, France.
Giorgia MangiliIRCCS San Raffaele Hospital, Vita-Salute University, Milan, Italy.
Philippe MoriceDepartment of Gynaecologic Surgery, Gustave-Roussy, Villejuif, France. Philippe.MORICE@gustaveroussy.fr.
Sébastien GouyDepartment of Gynaecologic Surgery, Gustave-Roussy, Villejuif, France.
Institut Gustave Roussy · FRBicêtre Hospital · FRIstituto di Ricovero e Cura a Carattere Scientifico San RaffaeleVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometrioid borderline ovarian tumor (EBOT) is a rare subtype of borderline ovarian malignancies. This study was designed to determine the prognosis of a series of EBOT.

methodsThis is a retrospective review of patients with EBOT treated in or referred to our institutions and a centralized, histological review by a reference pathologist. Data on the clinical characteristics, management (surgical and medical), and oncologic outcomes of patients were required for inclusion.

resultsForty-eight patients were identified. Median age was 52 years (range 14-89). Fourteen patients underwent a conservative surgery and 32 a bilateral salpingo-oophorectomy (unknown in 2 cases). Two patients had bilateral tumors. Forty-three patients had stage I disease, and five patients had stage II disease (10%). Stromal microinvasion and intraepithelial carcinoma was observed in 6 (12%) and 13 (27%) patients respectively. Endometriosis was histologically associated in 12 patients (25%). Synchronous endometrial disease was found in 7 (24%) of 29 patients with endometrial histological evaluation. The median follow-up was 72 months (range 6-146). Two patients developed a recurrence after cystectomy in form of borderline disease (5%). No death related to EBOT occurred.

conclusionsPeritoneal restaging surgery should be performed if not realized initially, because 5% of EBOTS are diagnosed at stage II-III. Fertility-sparing surgery seems a safe option in selected patients. Because synchronous endometrial diseases, including endometrial carcinoma are frequent, systematic hysterectomy (or endometrial sampling in case of fertility-sparing surgery) is mandatory. Prognosis is generally excellent. Recurrence is a rare event (6%), but it can occur in the form of invasive disease.

Indexed as

Endometrial NeoplasmsOvarian NeoplasmsAdolescentAdultAgedAged, 80 and overCystectomyFemaleHumansMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingPrognosisRetrospective StudiesYoung Adult

Identifiers

PMID35590116
OpenAlexW4280549082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.