Evidence map›Paper›PMID 35589980›Full record

ArticleArchives of orthopaedic and trauma surgery2022

Two-stage revision for periprosthetic joint infection in unicompartmental knee arthroplasty: clinical and radiological results.

Luca Cavagnaro, Francesco Chiarlone, Lorenzo Mosconi, Andrea Zanirato, Matteo Formica, Giorgio Burastero

Abstract read
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Periprosthetic Joint Infection WithCase reports in orthopedics · 2026
    Article
  3. DACBiomedicines · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luca CavagnaroJoint Replacement Unit/Bone Infection Unit, Ospedale Santa Corona, Via XXV Aprile 38, 17027, Pietra Ligure, SV, Italy. lucacavagnaro87@gmail.com.
Francesco ChiarloneJoint Replacement Unit/Bone Infection Unit, Ospedale Santa Corona, Via XXV Aprile 38, 17027, Pietra Ligure, SV, Italy.
Lorenzo MosconiJoint Replacement Unit/Bone Infection Unit, Ospedale Santa Corona, Via XXV Aprile 38, 17027, Pietra Ligure, SV, Italy.
Andrea ZaniratoOrthopaedic Department, Policlinico San Martino Largo, Rosanna Benzi 10, 16132, Genoa, GE, Italy.
Matteo FormicaOrthopaedic Department, Policlinico San Martino Largo, Rosanna Benzi 10, 16132, Genoa, GE, Italy.
Giorgio BurasteroJoint Replacement Unit, Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, MI, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUnicompartmental knee arthroplasty (UKA) has an infection rate of 0.1-0.8%. Despite the wide amount of literature about septic total knee arthroplasty management, few data are available for UKA infection treatment. The aim is to present the clinical and radiological outcomes along with complication rates of a series of septic UKA treated with two-stage exchange.

methodsWe retrospectively reviewed 16 patient treated with staged UKA revision for infection between June 2015 and September 2019 in a single bone infection unit. The main demographic and surgical data were recorded. Clinical scores (VAS, KSS, OKS, postoperative ROM), radiological parameters (osseointegration, loosening and radiolucencies) and complications were reported. The mean follow-up was 33.5 ± 6.9 months.

resultsMean age at surgery was 68.5 ± 9.1. All but two were medial UKA. The mean number of previous surgeries was 2.9 ± 1.9. The mean ROM, VAS, KSS and OKS of the entire population improved significantly (p < 0.01). Radiological analysis did not show any migration or implant loosening. Ten constrained condylar and six posterior stabilized prosthesis were finally implanted. One intraoperative pathogen isolation was recorded and managed with suppressive therapy and good final outcome. The implant survivorship free from infection was 100% at the final follow-up. The overall survival rate for any reason of revision was 100%

conclusionAccording to our results, staged revision represents a reliable ad effective option in delayed and late UKA infections. This technique provides optimal clinical and radiological results with acceptable complication rates. To the best of our knowledge, this represent the widest case series on infected UKA managed with two-stage exchange.

Indexed as

Arthritis, InfectiousArthroplasty, Replacement, KneeKnee ProsthesisOsteoarthritis, KneeProsthesis-Related InfectionsHumansKnee JointReoperationRetrospective StudiesTreatment OutcomeOutcomesPeriprosthetic joint infectionTwo-stage revisionUnicompartmental knee arthroplasty

Identifiers

PMID35589980
PMCPMC9296397

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.