ArticleNature communications2022
Fast raster-scan optoacoustic mesoscopy enables assessment of human melanoma microvasculature in vivo.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- S1 guideline for imaging diagnostics for skin diseases.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025Guideline
- Photoacoustic imaging for cutaneous melanoma assessment: a comprehensive review.Journal of biomedical optics · 2024Pooled it
- Real-time quality control in optoacoustic mesoscopy for enhancing data quality and standardization in clinical studies.Photoacoustics · 2026Article
- Optimization of light source parameters for photoacoustic imaging: trade-offs, technologies, and clinical considerations.JPhys photonics · 2026Review
- Photoacoustic Imaging in Immune-Mediated Inflammatory Skin Diseases: Diagnostic and Therapeutic Applications.Diagnostics (Basel, Switzerland) · 2026Review
- Hybrid Vision Transformer-CNN Architecture with Optimized Feature Selection for Skin Cancer Classification.Diagnostics (Basel, Switzerland) · 2026Article
- Ultrasound-Based Techniques for Visualization of Dermal Microvasculature: A Scoping Review.Diagnostics (Basel, Switzerland) · 2026Review
- Fully integrated photoacoustic microscopy for multi-scale and longitudinal imaging in translational biomedical applications.Biomedical optics express · 2026Article
- Label-free streamlined photoacoustic image guidance facilitates NIR-II photoablation in models of melanoma lung metastases.The Journal of clinical investigation · 2026Article
- Deep computational photoacoustic mesoscopy through heterogeneous tissues enabled by scanning compensation and angular-spectrum enhancement.Photoacoustics · 2026Article
- Tethered optoacoustic and optical coherence tomography capsule endoscopy for label-free assessment of Barrett's oesophageal neoplasia.Nature biomedical engineering · 2026Article
- Single-capillary endothelial dysfunction resolved by optoacoustic mesoscopy.Light, science & applications · 2026Article
- Optical and Optoacoustic Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
- Clinical translation of photoacoustic imaging using exogenous molecular contrast agents [Invited].Biomedical optics express · 2025Review
- Non-invasive characterization of melanoma depth at single-cell resolution.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025Article
- High-resolution three-dimensional quantitative photoacoustic and ultrasound imaging of subcutaneous microvasculature in extremities.Biomedical optics express · 2025Article
- Enhanced maximum intensity projection (eMIP) for improving the fidelity of optoacoustic images.Npj imaging · 2025Article
- Fibrotic Disease: from Signaling Pathways and Biomarkers to Molecular Imaging.Molecular imaging and biology · 2025Review
- Artifacts in photoacoustic imaging: Origins and mitigations.Photoacoustics · 2025Article
- A primer on current status and future opportunities of clinical optoacoustic imaging.Npj imaging · 2025Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melanoma is associated with angiogenesis and vascular changes that may extend through the entire skin depth. Three-dimensional imaging of vascular characteristics in skin lesions could therefore allow diagnostic insights not available by conventional visual inspection. Raster-scan optoacoustic mesoscopy (RSOM) images microvasculature through the entire skin depth with resolutions of tens of micrometers; however, current RSOM implementations are too slow to overcome the strong breathing motions on the upper torso where melanoma lesions commonly occur. To enable high-resolution imaging of melanoma vasculature in humans, we accelerate RSOM scanning using an illumination scheme that is coaxial with a high-sensitivity ultrasound detector path, yielding 15 s single-breath-hold scans that minimize motion artifacts. We apply this Fast RSOM to image 10 melanomas and 10 benign nevi in vivo, showing marked differences between malignant and benign lesions, supporting the possibility to use biomarkers extracted from RSOM imaging of vasculature for lesion characterization to improve diagnostics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.