Evidence map›Paper›PMID 35589709›Full record

ArticleNature communications2022

Elimination of human rabies in Goa, India through an integrated One Health approach.

A D Gibson, G Yale, J Corfmat, M Appupillai, C M Gigante, M Lopes, U Betodkar, N C Costa, K A Fernandes, P Mathapati and 21 more

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Rabies post-exposure prophylaxis in India: a SWOT analysis.Therapeutic advances in vaccines and immunotherapy · 2026
    Review
  10. Article
  11. Review
  12. Review
  13. Rabies elimination in India: Pathways from vision to reality.The Indian journal of medical research · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

A D Gibson *Mission Rabies, Cranborne, Dorset, United Kingdom. andy@missionrabies.com.ORCID 0000-0002-4641-2583
G Yale *Mission Rabies, Tonca, Panjim, Goa, India.
J Corfmat *Mission Rabies, Tonca, Panjim, Goa, India.
M Appupillai *Mission Rabies, Tonca, Panjim, Goa, India.
C M GigantePoxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
M LopesDepartment of Animal Husbandry & Veterinary Services, Government of Goa, Panaji, India.
U BetodkarDirectorate of Health Services, Government of Goa, Panaji, India.
N C CostaDepartment of Animal Husbandry & Veterinary Services, Government of Goa, Panaji, India.
K A FernandesWorldwide Veterinary Service India, Ooty, Tamil Nadu, India.
P MathapatiMission Rabies, Tonca, Panjim, Goa, India.
P M SuryawanshiDirectorate of Health Services, Government of Goa, Panaji, India.
N OtterMission Rabies, Tonca, Panjim, Goa, India.
G ThomasMission Rabies, Cranborne, Dorset, United Kingdom.
P OhalMission Rabies, Tonca, Panjim, Goa, India.
I Airikkala-OtterWorldwide Veterinary Service India, Ooty, Tamil Nadu, India.
F LohrMission Rabies, Cranborne, Dorset, United Kingdom.ORCID 0000-0002-7158-3122
C E RupprechtLYSSA LLC, Atlanta, Georgia, United States.
A KingMerck Animal Health, Madison, NJ, USA.
D SuttonMSD Animal Health, Walton Manor, Walton, Milton Keynes, MK7 7AJ, United Kingdom.
I DeuzemanMerck Animal Health, Madison, NJ, USA.
Y LiPoxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0001-8815-6816
R M WallacePoxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
R S ManiDepartment of Neurovirology, WHO Collaborating Centre for Reference and Research in Rabies, National Institute of Mental Health and Neurosciences, Bengaluru, India.
G GongalWHO Regional Office for South East Asia, New Delhi, India.
I G HandelThe Roslin Institute and The Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom.
M BronsvoortThe Roslin Institute and The Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom.ORCID 0000-0002-3271-8485
V NaikDepartment of Animal Husbandry & Veterinary Services, Government of Goa, Panaji, India.
S DesaiDepartment of Animal Husbandry & Veterinary Services, Government of Goa, Panaji, India.
S MazeriMission Rabies, Cranborne, Dorset, United Kingdom.
L GambleMission Rabies, Cranborne, Dorset, United Kingdom.
R J MellanbyThe Roslin Institute and The Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom.

Funding

Biotechnology and Biological Sciences Research Council BB/J004235/1Biotechnology and Biological Sciences Research Council BB/P013740/1World Health Organization 001
6 · The paper itself

Abstract

Dog-mediated rabies kills tens of thousands of people each year in India, representing one third of the estimated global rabies burden. Whilst the World Health Organization (WHO), World Organization for Animal Health (OIE) and the Food and Agriculture Organization of the United Nations (FAO) have set a target for global dog-mediated human rabies elimination by 2030, examples of large-scale dog vaccination programs demonstrating elimination remain limited in Africa and Asia. We describe the development of a data-driven rabies elimination program from 2013 to 2019 in Goa State, India, culminating in human rabies elimination and a 92% reduction in monthly canine rabies cases. Smartphone technology enabled systematic spatial direction of remote teams to vaccinate over 95,000 dogs at 70% vaccination coverage, and rabies education teams to reach 150,000 children annually. An estimated 2249 disability-adjusted life years (DALYs) were averted over the program period at 526 USD per DALY, making the intervention 'very cost-effective' by WHO definitions. This One Health program demonstrates that human rabies elimination is achievable at the state level in India.

Indexed as

Dog DiseasesOne HealthRabiesAnimalsCost-Benefit AnalysisDogsHumansIndia

Identifiers

PMID35589709
PMCPMC9120018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.