Evidence map›Paper›PMID 35589688›Full record

ArticleOncogenesis2022

Estradiol-mediated inhibition of DNMT1 decreases p53 expression to induce M2-macrophage polarization in lung cancer progression.

Yung-Ching Chen, Ming-Jer Young, Hui-Ping Chang, Chia-Yu Liu, Chia-Chi Lee, Yau-Lin Tseng, Yi-Ching Wang, Wen-Chang Chang, Jan-Jong Hung

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncogenesis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yung-Ching Chen *Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan.
Ming-Jer Young *Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan.ORCID http://orcid.org/0000-0003-2638-6813
Hui-Ping ChangDepartment of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan.
Chia-Yu LiuDepartment of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan.
Chia-Chi LeeDivision of Thoracic Surgery, Department of Surgery, College of Medicine National Cheng Kung University, Tainan, Taiwan.
Yau-Lin TsengDivision of Thoracic Surgery, Department of Surgery, College of Medicine National Cheng Kung University, Tainan, Taiwan.
Yi-Ching WangDepartment of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.ORCID http://orcid.org/0000-0002-7694-2067
Wen-Chang ChangThe Ph.D. Program for Neural Regenerative Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-1801-553X
Jan-Jong HungDepartment of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan. petehung@mail.ncku.edu.tw.ORCID http://orcid.org/0000-0001-5772-8877
National Cheng Kung University · TWTaipei Medical University · TW

Funding

Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) 106-2320-B-006-065-MY3Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) 108-2320-B-006-019Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) 109-2320-B-006-057
6 · The paper itself

Abstract

Previous studies indicate that estrogen positively regulates lung cancer progression. Understanding the reasons will be beneficial for treating women with lung cancer in the future. In this study, we found that tumor formation was more significant in female EGFR

Identifiers

PMID35589688
PMCPMC9119954
OpenAlexW4280647320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.