Evidence map›Paper›PMID 35589407›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

First-in-Humans PET Imaging of Tissue Factor in Patients with Primary and Metastatic Cancers Using

Mathias Loft, Camilla Christensen, Malene M Clausen, Esben A Carlsen, Carsten P Hansen, Niels Kroman, Seppo W Langer, Claus Høgdall, Jacob Madsen, Nic Gillings and 6 more

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Advances in PET/CT Imaging for Breast Cancer.Journal of clinical medicine · 2023
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Mathias LoftDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Camilla ChristensenDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Malene M ClausenDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Esben A CarlsenDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Carsten P HansenDepartment of Surgery, Copenhagen University Hospital - Rigshospitalet, Denmark.
Niels KromanDepartment of Breast Surgery, Copenhagen University Hospital - Rigshospitalet, Denmark.
Seppo W LangerDepartment of Oncology, Copenhagen University Hospital - Rigshospitalet, Denmark.
Claus HøgdallDepartment of Gynecology, Copenhagen University Hospital - Rigshospitalet, Denmark and.
Jacob MadsenDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Nic GillingsDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Carsten H NielsenDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Thomas L KlausenDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Søren HolmDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Annika LoftDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Anne K BerthelsenDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark.
Andreas KjaerDepartment of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, Denmark; akjaer@sund.ku.dk.
Rigshospitalet · DKCopenhagen University Hospital · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue factor (TF) expression in cancers correlates with poor prognosis. Recently, the first TF-targeted therapy was approved by the U.S. Food and Drug Administration for cervical cancer. To unfold the potential of TF-targeted therapies, correct stratification and selection of patients eligible for treatments may become important for optimization of patient outcomes. TF-targeted PET imaging based on

Indexed as

Neoplasms, Second PrimaryUterine Cervical NeoplasmsFactor VIIFemaleHumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiometryThromboplastinTissue DistributionFactor VIIThromboplastinactive site inhibited factor VII (ASIS)first-in-humansPET/CTphase I clinical trialtissue factor

Identifiers

PMID35589407
PMCPMC9730914
OpenAlexW4281249635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.