Evidence map›Paper›PMID 35589236›Full record

ArticleJACC. Cardiovascular interventions2022

Comparison of Doppler Flow Velocity and Thermodilution Derived Indexes of Coronary Physiology.

Ozan M Demir, Coen K M Boerhout, Guus A de Waard, Tim P van de Hoef, Niket Patel, Marcel A M Beijk, Rupert Williams, Haseeb Rahman, Henk Everaars, Oxford Acute Myocardial Infarction (OxAMI) Study and 5 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in JACC. Cardiovascular interventions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Systematic review and meta-analysis of Murray's law in the coronary arterial circulation.American journal of physiology. Heart and circulatory physiology · 2024
    Pooled it
  2. Reproducibility of bolus versus continuous thermodilution for assessment of coronary microvascular function in patients with ANOCA.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Trial
  3. Review
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  6. Article
  7. Article
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  9. Observational
  10. Article
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  13. Review
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  16. Developing a Women's Heart Center With a Specialization in Coronary Microvascular and Vasomotor Dysfunction: If You Build It, They Will Come.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2024
    Review
  17. Utilizing Invasive Coronary Functional Testing in a Coronary Microvascular and Vasomotor Dysfunction Program: Methods and Considerations.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2024
    Article
  18. Article
  19. When Is It a Bridge Too Far?Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Ozan M DemirBritish Heart Foundation Centre of Excellence and National Institute for Health Research Biomedical Research Centre at the School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom.
Coen K M BoerhoutDepartment of Clinical and Experimental Cardiology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Guus A de WaardDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands.
Tim P van de HoefDepartment of Clinical and Experimental Cardiology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Niket PatelOxford Heart Centre, Oxford University Hospitals, Oxford, United Kingdom.
Marcel A M BeijkDepartment of Clinical and Experimental Cardiology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Rupert WilliamsBritish Heart Foundation Centre of Excellence and National Institute for Health Research Biomedical Research Centre at the School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom.
Haseeb RahmanBritish Heart Foundation Centre of Excellence and National Institute for Health Research Biomedical Research Centre at the School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom.
Henk EveraarsDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands.
Oxford Acute Myocardial Infarction (OxAMI) StudyOxford Heart Centre, Oxford University Hospitals, Oxford, United Kingdom.
Rajesh K KharbandaOxford Heart Centre, Oxford University Hospitals, Oxford, United Kingdom.
Paul KnaapenDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands.
Niels van RoyenDepartment of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Jan J PiekDepartment of Clinical and Experimental Cardiology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Divaka PereraBritish Heart Foundation Centre of Excellence and National Institute for Health Research Biomedical Research Centre at the School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom. Electronic address: divaka.perera@kcl.ac.uk.
University of Amsterdam · NLAmsterdam UMC Location VUmc · NLKing's College London · GBOxford University Hospitals NHS Trust · GBBritish Heart Foundation · GBNIHR Biomedical Research Centre at The Royal Marsden and the ICRRadboud University Medical Center · NL

Funding

British Heart Foundation FS/16/49/32320British Heart Foundation PG/19/9/34228
6 · The paper itself

Abstract

objectivesThe aim of this study was to compare Doppler flow velocity and thermodilution-derived indexes and to determine the optimal thermodilution-based diagnostic thresholds for coronary flow reserve (CFR).

backgroundThe majority of clinical data and diagnostic thresholds for flow-based indexes are derived from Doppler measurements, and correspondence with thermodilution-derived indices remain unclear.

methodsAn international multicenter registry was conducted among patients who had coronary flow measurements using both Doppler and thermodilution techniques in the same vessel and during the same procedure.

resultsPhysiological data from 250 vessels (in 149 patients) were included in the study. A modest correlation was found between thermodilution-derived CFR (CFR

conclusionsCFR calculated by thermodilution overestimates Doppler-derived CFR, while both parameters show modest correlation. The commonly used CFR

Indexed as

HyperemiaThermodilutionBlood Flow VelocityCoronary CirculationCoronary VesselsHumansMicrocirculationTreatment Outcomecoronary flow reservehyperemic microvascular resistanceindex of microvascular resistancemicrovascular dysfunction

Identifiers

PMID35589236
PMCPMC9126183
OpenAlexW4280547074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.