ArticleCerebral cortex (New York, N.Y. : 1991)2023
Sulcal depth in prefrontal cortex: a novel predictor of working memory performance.
Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 63 citations in OpenAlex.
- Twelve weeks of physical exercise breaks with coordinative exercises at the workplace increase the sulcal depth and decrease gray matter volume in brain structures related to visuomotor processes.Brain structure & function · 2024Trial
- Sulcal anatomy of ventral temporal cortex and reading development.bioRxiv : the preprint server for biology · 2026Article
- Genetic insights on the mechanisms of human cortical folding.bioRxiv : the preprint server for biology · 2026Article
- How do infant brains fold? Sulcal deepening is linked to development of sulcal span, thickness, curvature, and microstructure.Communications biology · 2026Article
- The inferior frontal sulcus in the chimpanzee brain: morphological examination and association with oro-facial communication.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Variable Presence of an Evolutionarily New Brain Structure Is Related to Trait Impulsivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Music participation, global cortical morphometry, and later language outcomes in the ABCD study.Frontiers in psychology · 2026Article
- Anchoring Functional Connectivity to Individual Sulcal Morphology Yields Insights in a Pediatric Study of Reasoning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Anchoring functional connectivity to individual sulcal morphology yields insights in a pediatric study of reasoning.bioRxiv : the preprint server for biology · 2025Article
- A Self-supervised Deep Learning Model for Diagonal Sulcus Detection with Limited Labeled Data.Neuroinformatics · 2025Article
- Cortical morphology changes in default mode network regions as predictors of cognitive decline in relation to amyloid and tau deposits.Brain communications · 2025Article
- Alterations in sulcal depth and associated functional connectivity in schizophrenia with auditory verbal hallucinations.Frontiers in psychiatry · 2025Article
- Local gyrification index and sulcal depth as imaging markers of cognitive decline in Alzheimer's disease.Frontiers in aging neuroscience · 2025Article
- Flight training and alterations in cortical characteristics.Frontiers in human neuroscience · 2025Article
- Differences in structural brain morphometry between musicians and non-musicians.Frontiers in human neuroscience · 2025Article
- Emotion-related impulsivity is related to orbitofrontal cortical sulcation.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Defining putative tertiary sulci in lateral prefrontal cortex in chimpanzees using human predictions.Brain structure & function · 2024Article
- Variable Presence of an Evolutionarily New Brain Structure is Related to Trait Impulsivity.bioRxiv : the preprint server for biology · 2024Article
- Article
- An MRI Study of Morphology, Asymmetry, and Sex Differences of Inferior Precentral Sulcus.Brain topography · 2024Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The neuroanatomical changes that underpin cognitive development are of major interest in neuroscience. Of the many aspects of neuroanatomy to consider, tertiary sulci are particularly attractive as they emerge last in gestation, show a protracted development after birth, and are either human- or hominoid-specific. Thus, they are ideal targets for exploring morphological-cognitive relationships with cognitive skills that also show protracted development such as working memory (WM). Yet, the relationship between sulcal morphology and WM is unknown-either in development or more generally. To fill this gap, we adopted a data-driven approach with cross-validation to examine the relationship between sulcal depth in lateral prefrontal cortex (LPFC) and verbal WM in 60 children and adolescents between ages 6 and 18. These analyses identified 9 left, and no right, LPFC sulci (of which 7 were tertiary) whose depth predicted verbal WM performance above and beyond the effect of age. Most of these sulci are located within and around contours of previously proposed functional parcellations of LPFC. This sulcal depth model outperformed models with age or cortical thickness. Together, these findings build empirical support for a classic theory that tertiary sulci serve as landmarks in association cortices that contribute to late-maturing human cognitive abilities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.