Evidence map›Paper›PMID 35588742›Full record

ArticleCurrent biology : CB2022

Ancient Maltese genomes and the genetic geography of Neolithic Europe.

Bruno Ariano, Valeria Mattiangeli, Emily M Breslin, Eóin W Parkinson, T Rowan McLaughlin, Jess E Thompson, Ronika K Power, Jay T Stock, Bernardette Mercieca-Spiteri, Simon Stoddart and 4 more

Open access · hybridAbstract readHistorical Article
In one paragraph

Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 6 countries.

Bruno ArianoSmurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.
Valeria MattiangeliSmurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.
Emily M BreslinSmurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.
Eóin W ParkinsonDepartment of Classics and Archaeology, University of Malta, Msida 2080, Malta.
T Rowan McLaughlinDepartment of Scientific Research, The British Museum, Great Russell Street, London WC1B 3DG, UK.
Jess E ThompsonMcDonald Institute for Archaeological Research, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.
Ronika K PowerDepartment of History and Archaeology, Macquarie University, 25B Wally's Walk, Sydney, NSW, Australia.
Jay T StockDepartment of Anthropology, Western University, 1151 Richmond St, London, ON N6G 2V4, Canada.
Bernardette Mercieca-SpiteriSuperintendence of Cultural Heritage, St Christopher Street, Valletta 2000, Malta.
Simon StoddartMcDonald Institute for Archaeological Research, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.
Caroline MaloneSchool of Natural and Built Environment, Queen's University Belfast, Elmwood Avenue, Belfast, UK.
Shyam GopalakrishnanGLOBE Institute, University of Copenhagen, Øster Farimagsgade 5, 1353 København K, Denmark. Electronic address: fck245@ku.dk.
Lara M CassidySmurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland. Electronic address: cassidsl1@tcd.ie.
Daniel G BradleySmurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland. Electronic address: dbradley@tcd.ie.
Trinity College Dublin · IEUniversity of Cambridge · GBBritish Museum · GBHeritage Malta · MTMacquarie University · AUQueen's University Belfast · GBUniversity of Copenhagen · DKUniversity of Malta · MTWestern University · CA

Funding

Wellcome Trust 205072Wellcome Trust 205072/Z/16/Z
6 · The paper itself

Abstract

Archaeological consideration of maritime connectivity has ranged from a biogeographical perspective that considers the sea as a barrier to a view of seaways as ancient highways that facilitate exchange. Our results illustrate the former. We report three Late Neolithic human genomes from the Mediterranean island of Malta that are markedly enriched for runs of homozygosity, indicating inbreeding in their ancestry and an effective population size of only hundreds, a striking illustration of maritime isolation in this agricultural society. In the Late Neolithic, communities across mainland Europe experienced a resurgence of hunter-gatherer ancestry, pointing toward the persistence of different ancestral strands that subsequently admixed. This is absent in the Maltese genomes, giving a further indication of their genomic insularity. Imputation of genome-wide genotypes in our new and 258 published ancient individuals allowed shared identity-by-descent segment analysis, giving a fine-grained genetic geography of Neolithic Europe. This highlights the differentiating effects of seafaring Mediterranean expansion and also island colonization, including that of Ireland, Britain, and Orkney. These maritime effects contrast profoundly with a lack of migratory barriers in the establishment of Central European farming populations from Anatolia and the Balkans.

Indexed as

ArchaeologyGenome, HumanAgricultureDNA, AncientDNA, MitochondrialEuropeGeographyHistory, AncientHuman MigrationHumansDNA, AncientDNA, Mitochondrialancient DNAisland archaeologymigrationNeolithicpopulation genomics

Identifiers

PMID35588742
PMCPMC9245899
OpenAlexW4280653123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.