Evidence map›Paper›PMID 35588734›Full record

ArticleCell reports. Medicine2022

TNF-α

Kattria van der Ploeg, Adam S Kirosingh, Diego A M Mori, Saborni Chakraborty, Zicheng Hu, Benjamin L Sievers, Karen B Jacobson, Hector Bonilla, Julie Parsonnet, Jason R Andrews and 12 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports. Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. CD4Science advances · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 1 country.

Kattria van der PloegDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Adam S KirosinghDepartment of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA.
Diego A M MoriDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Saborni ChakrabortyDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Zicheng HuDepartment of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143, USA; Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA 94143, USA.
Benjamin L SieversJ. Craig Venter Institute, La Jolla, CA 92037, USA.
Karen B JacobsonDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Hector BonillaDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Julie ParsonnetDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Epidemiology and Population Health, Stanford University, Stanford, CA 94305, USA.
Jason R AndrewsDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Kathleen D PressDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Maureen C TyDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Daniel R Ruiz-BetancourtDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Lauren de la ParteDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Gene S TanJ. Craig Venter Institute, La Jolla, CA 92037, USA; Division of Infectious Disease, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Catherine A BlishDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.
Saki TakahashiDepartment of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.
Isabel Rodriguez-BarraquerDepartment of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.
Bryan GreenhouseChan Zuckerberg Biohub, San Francisco, CA 94158, USA; Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.
Upinder SinghDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA.
Taia T WangDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA.
Prasanna JagannathanDepartment of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA. Electronic address: prasj@stanford.edu.
Stanford University · USUniversity of California, San Francisco · USJ. Craig Venter Institute · USChan Zuckerberg Initiative (United States) · US

Funding

Using a tonsil organoid system to probe conditions for the induction of protective antibody and T cell responses to influenza.U19AI057229 · NIAID · STANFORD UNIVERSITY · PI Mark Morris Davis · 2003 to 2026
$88.5M
Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
Computational models of naturally acquired immunity to falciparum malariaU01AI150741 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUTTE, ATUL J, GREENHOUSE, BRYAN R · 2020 to 2024
$7.4M
EMERGING INFECTIOUS DISEASEST32AI007502 · NIAID · STANFORD UNIVERSITY · PI Prasanna Jagannathan, DAVID A. RELMAN · 1995 to 2026
$6.8M
Global Epidemiology of Infectious DiseasesT32AI052073 · NIAID · STANFORD UNIVERSITY · PI Angelle Desiree LaBeaud, Stephen Patrick Luby · 2003 to 2026
$4.2M
Mentoring translational scientists in international infectious disease researchK24AI144048 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Bryan R Greenhouse · 2019 to 2026
$1.6M
Translational Studies of Plasmodium Falciparum Infection DynamicsK23AI076614 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GREENHOUSE, BRYAN R · 2008 to 2012
$609k
NCATS NIH HHS UL1 TR001085NCATS NIH HHS UL1 TR003142NIAID NIH HHS K23 AI076614NIAID NIH HHS K24 AI144048NIAID NIH HHS T32 AI007502NIAID NIH HHS T32 AI052073NIAID NIH HHS U01 AI150741NIAID NIH HHS U19 AI057229
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific CD4

Indexed as

COVID-19SARS-CoV-2Antibodies, NeutralizingCD4-Positive T-LymphocytesHumansOutpatientsT-LymphocytesTumor Necrosis Factor-alphaAntibodies, NeutralizingTumor Necrosis Factor-alphaantibodiesCD4COVID-19cytokineslongitudinalneutralizing antibodiesSARS-CoV-2T cellsTfhTNF-α

Identifiers

PMID35588734
PMCPMC9061140
OpenAlexW4225379921

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.