ArticleBlood advances2022
Epigenome-wide association study of acute lymphoblastic leukemia in children with Down syndrome.
Open access · goldAbstract read
In one paragraph
Article in Blood advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- The Unique Utility of Newborn Dried Blood Spots for Driving Discovery in Childhood Cancer Research.Clinical chemistry · 2025Review
- Comprehensive Epigenome-Wide Profiling Reveals Distinctive DNA Methylation Signatures and Potential Prognostic Biomarkers in Mexican Pediatric B-ALL.International journal of molecular sciences · 2025Article
- Gain of chromosome 21 increases the propensity forFrontiers in oncology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 7 institutions in 2 countries.
Shaobo LiCenter for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA.ORCID 0000-0002-0544-5338
Pagna SokDepartment of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX.
Keren XuCenter for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA.ORCID 0000-0003-4615-2459
Ivo S MuskensCenter for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA.
Natalina ElliottDepartment of Paediatrics and MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Oxford University and BRC Blood Theme, NIHR Oxford Biomedical Centre, Oxford, UK.
Swe Swe MyintCenter for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA.ORCID 0000-0002-2430-088X
Priyatama PandeyCenter for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA.
Helen M HansenDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA.ORCID 0000-0001-5456-4985
Libby M MorimotoSchool of Public Health, University of California, Berkeley, Berkeley, CA.ORCID 0000-0002-1509-739X
Alice Y KangSchool of Public Health, University of California, Berkeley, Berkeley, CA.
Catherine MetayerSchool of Public Health, University of California, Berkeley, Berkeley, CA.
Xiaomei MaDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT.
Beth A MuellerPublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA; and.
Anindita RoyDepartment of Paediatrics and MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Oxford University and BRC Blood Theme, NIHR Oxford Biomedical Centre, Oxford, UK.
Irene RobertsDepartment of Paediatrics and MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Oxford University and BRC Blood Theme, NIHR Oxford Biomedical Centre, Oxford, UK.
Karen R RabinDepartment of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX.ORCID 0000-0002-4081-8195
Austin L BrownDepartment of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX.ORCID 0000-0001-5802-5073
Philip J LupoDepartment of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX.ORCID 0000-0003-0978-5863
Joseph L WiemelsCenter for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA.
Adam J de SmithCenter for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA.ORCID 0000-0003-4880-7543
University of Southern California · USBaylor College of Medicine · USBerkeley Public Health Division · USUniversity of Oxford · GBUniversity of California, San Francisco · USUniversity of Washington · USYale University · US
Funding
Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MCHALE, CLIONA · 1987 to 2025
$74.6MCALIFORNIA COORDINATED CANCER PREVENTION & CONTROL PROGRAMU58DP003862 · DP · CALIFORNIA STATE DEPT OF PUBLIC HEALTH · PI SNIPES, KURT P · 2012 to 2014
$31.5MEnvironmental and Molecular Epidemiology of Childhood LeukemiaR01ES009137 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI METAYER, CATHERINE · 1999 to 2013
$21.1MMolecular epidemiology of acute lymphoblastic leukemia in children with Down syndromeR01CA249867 · NCI · BAYLOR COLLEGE OF MEDICINE · PI LUPO, PHILIP, RABIN, KAREN R · 2020 to 2024
$4.2MPerinatal immune development and risk of childhood acute lymphoblastic leukemiaR01CA175737 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MA, XIAOMEI, WIEMELS, JOSEPH LEO · 2014 to 2018
$3.0MSupport For Infrastructure of Childhood Leukemia Environmental ResearchR24ES028524 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Catherine Metayer · 2017 to 2026
$2.3MMedical Research Council MC_UU_00029/7Medical Research Council MC_UU_12009/14Medical Research Council MR/R006237/1NCCDPHP CDC HHS U58 DP003862NCI NIH HHS HHSN261201000034CNCI NIH HHS HHSN261201000035CNCI NIH HHS HHSN261201000035INCI NIH HHS HHSN261201000140CNCI NIH HHS R01 CA175737NCI NIH HHS R01 CA249867NIEHS NIH HHS P42 ES004705NIEHS NIH HHS R01 ES009137NIEHS NIH HHS R24 ES028524
Abstract
PubMed holds no abstract for this paper.
Indexed as
Down SyndromePrecursor Cell Lymphoblastic Leukemia-LymphomaAcute DiseaseChildEpigenomeHumans
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.