ArticleClinical and translational medicine2022
Lipids and genes: Regulatory roles of lipids in RNA expression.
Article in Clinical and translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Trial
- Investigating FTY720-NF immunomodulation of key lipid, gene, and protein mediators to enhance oral tissue regeneration.Biomaterials advances · 2026Article
- Apolipoproteins L involvement in immunity.Journal of human immunity · 2026Review
- Integrated Symbiotic Pleiotropy: Long Non-Coding RNAs and Disordered Proteins Interweaving the Functional Layers of the Eukaryotic Cell.International journal of molecular sciences · 2026Review
- Chronic alcohol intake elicits distinct multi-omic profiles in the liverbioRxiv : the preprint server for biology · 2025Article
- Phase separation of a master transcription factor targeted by a natural compound regulates fungal ergosterol homeostasis.Science China. Life sciences · 2025Article
- Cannabidiol abrogates cue-induced anxiety associated with normalization of mitochondria-specific transcripts and linoleic acid in the nucleus accumbens shell.Molecular psychiatry · 2025Article
- Oxylipins in Breast Implant-Associated Systemic Symptoms.Aesthetic surgery journal · 2024Article
- Integration of clinical phenoms and metabolomics facilitates precision medicine for lung cancer.Cell biology and toxicology · 2024Article
- [Modified styrene-maleic anhydride copolymer-based chromatographic stationary phase for phospholipid separation and analysis].Se pu = Chinese journal of chromatography · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nuclear lipid metabolism and metabolites play important roles in regulation of lipid-lipid, lipid-gene, lipid-chromatin, lipid-membrane and lipid-protein interactions to maintain the nuclear microenvironment, three-dimensional chromatin architecture, gene expression and transcription and biological function. This Editorial highlights the value of lipid-gene interaction in the identification and development of biomarkers and targets and emphasizes the significance of inter-regulation between lipids and genes in innovation and application of precise therapies for patients. Regulatory functions of nuclear lipid dynamics and biophysics modify transcriptomic expression, and modification (lipotranscriptome) can be a new approach for discovery and development of disease-specific diagnoses and therapies, although there are several challenges to be overcome. Better understanding of how lipid-based changes of nuclear functions and transcriptomic profiles modify clinical phenomes will provide new insights to understand molecular mechanisms of diseases and to develop spatiotemporal molecular medicine diagnostics and therapeutics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.