Evidence map›Paper›PMID 35588288›Full record

ArticleMedical physics2022

Four-dimensional computed tomography of the left ventricle, Part I: Motion artifact reduction.

Jed D Pack, Ashish Manohar, Sathish Ramani, Bernhard Claus, Zhye Yin, Francisco J Contijoch, Andrew J Schluchter, Elliot R McVeigh

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. 3D regional evaluation of right ventricular myocardial work from cineCT.medRxiv : the preprint server for health sciences · 2024
    Article
  3. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jed D PackRadiation Systems Lab, GE Global Research, Niskayuna, New York, USA.
Ashish ManoharDepartment of Mechanical and Aerospace Engineering, UC San Diego School of Engineering, La Jolla, California, USA.
Sathish RamaniRadiation Systems Lab, GE Global Research, Niskayuna, New York, USA.
Bernhard ClausRadiation Systems Lab, GE Global Research, Niskayuna, New York, USA.
Zhye YinRadiation Systems Lab, GE Global Research, Niskayuna, New York, USA.
Francisco J ContijochDepartment of Bioengineering, UC San Diego School of Engineering, La Jolla, California, USA.
Andrew J SchluchterDepartment of Bioengineering, UC San Diego School of Engineering, La Jolla, California, USA.
Elliot R McVeighDepartment of Bioengineering, UC San Diego School of Engineering, La Jolla, California, USA.
GE Global Research (United States) · USUniversity of California, San Diego · USUC San Diego Health System · US

Funding

Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1M
True 4DCT for Quantifying LV Dyssynchrony and Function for Targeting LV Lead Location in CRTR01HL144678 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCVEIGH, ELLIOT R · 2019 to 2022
$3.3M
UCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3M
Patient-specific thrombosis risk in atrial fibrillation by 4D CT imaging of atrial kinetics combined with computational fluid dynamicsR01HL160024 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEL ALAMO, JUAN CARLOS, KAHN, ANDREW · 2021 to 2024
$2.7M
NHLBI NIH HHS R01 HL144678NHLBI NIH HHS R01 HL160024NHLBI NIH HHS R25 HL145817NHLBI NIH HHS T32 HL007444NIH HHS R01 HL144678
6 · The paper itself

Abstract

purposeStandard four-dimensional computed tomography (4DCT) cardiac reconstructions typically include spiraling artifacts that depend not only on the motion of the heart but also on the gantry angle range over which the data was acquired. We seek to reduce these motion artifacts and, thereby, improve the accuracy of left ventricular wall positions in 4DCT image series.

methodsWe use a motion artifact reduction approach (ResyncCT) that is based largely on conjugate pairs of partial angle reconstruction (PAR) images. After identifying the key locations where motion artifacts exist in the uncorrected images, paired subvolumes within the PAR images are analyzed with a modified cross-correlation function in order to estimate 3D velocity and acceleration vectors at these locations. A subsequent motion compensation process (also based on PAR images) includes the creation of a dense motion field, followed by a backproject-and-warp style compensation. The algorithm was tested on a 3D printed phantom, which represents the left ventricle (LV) and on challenging clinical cases corrupted by severe artifacts.

resultsThe results from our preliminary phantom test as well as from clinical cardiac scans show crisp endocardial edges and resolved double-wall artifacts. When viewed as a temporal series, the corrected images exhibit a much smoother motion of the LV endocardial boundary as compared to the uncorrected images. In addition, quantitative results from our phantom studies show that ResyncCT processing reduces endocardial surface distance errors from 0.9 ± 0.8 to 0.2 ± 0.1 mm.

conclusionsThe ResyncCT algorithm was shown to be effective in reducing motion artifacts and restoring accurate wall positions. Some perspectives on the use of conjugate-PAR images and on techniques for CT motion artifact reduction more generally are also given.

Indexed as

ArtifactsFour-Dimensional Computed TomographyAlgorithmsHeart VentriclesMotionPhantoms, Imaging4DCTcardiac CTmotion correction

Identifiers

PMID35588288
PMCPMC11088001
OpenAlexW4280555795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.