Evidence map›Paper›PMID 35588273›Full record

ArticleApplied and environmental microbiology2022

Synergistic Inactivation of African Swine Fever Virus by a Highly Complexed Iodine Combined with Compound Organic Acids.

Mengnan Qi, Li Pan, Ying Gao, Miao Li, Yanjin Wang, Lian-Feng Li, Chen Ji, Yuan Sun, Hua-Ji Qiu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mengnan Qi *State Key Laboratory of Veterinary Biotechnology, National High-Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institutegrid.38587.31, Chinese Academy of Agricultural Sciences, Harbin, China.
Li Pan *State Key Laboratory of Veterinary Biotechnology, National High-Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institutegrid.38587.31, Chinese Academy of Agricultural Sciences, Harbin, China.
Ying GaoState Key Laboratory of Veterinary Biotechnology, National High-Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institutegrid.38587.31, Chinese Academy of Agricultural Sciences, Harbin, China.
Miao LiState Key Laboratory of Veterinary Biotechnology, National High-Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institutegrid.38587.31, Chinese Academy of Agricultural Sciences, Harbin, China.
Yanjin WangState Key Laboratory of Veterinary Biotechnology, National High-Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institutegrid.38587.31, Chinese Academy of Agricultural Sciences, Harbin, China.
Lian-Feng LiState Key Laboratory of Veterinary Biotechnology, National High-Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institutegrid.38587.31, Chinese Academy of Agricultural Sciences, Harbin, China.
Chen JiGuangdong Ruiji Biotechnology Co., Ltd., Huizhou, China.
Yuan SunState Key Laboratory of Veterinary Biotechnology, National High-Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institutegrid.38587.31, Chinese Academy of Agricultural Sciences, Harbin, China.
Hua-Ji QiuState Key Laboratory of Veterinary Biotechnology, National High-Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institutegrid.38587.31, Chinese Academy of Agricultural Sciences, Harbin, China.ORCID 0000-0003-4880-5687
Chinese Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African swine fever (ASF) is a highly contagious disease of domestic pigs and wild boar with high morbidity and mortality caused by African swine fever virus (ASFV). Due to the lack of commercial vaccines and treatments for ASF, cleaning and disinfection remain one of the most effective biosecurity measures to control ASF. Our previous studies have shown that ASFV can be inactivated by 0.25 to 5% highly complexed iodine (HPCI) in 5 to 30 min. This study evaluated the synergistic inactivation effects of HPCI combined with compound organic acids (COAs) against ASFV. The results showed that the inactivation rates of HPCI, COAs, and HPCI+COAs on the reporter ASFV expressing the green fluorescent protein increased in dose- and time-dependent manners. The best inactivation effects were obtained when the compatibility ratio of HPCI and COAs was 5:1, and the ideal temperature was 25°C. Furthermore, there were no significant differences when comparing the efficacy of HPCI combined with COAs (HPCI+COAs) in inactivating wild-type ASFV and the reporter ASFV (

Indexed as

African Swine FeverAfrican Swine Fever VirusDisinfectantsIodineAnimalsSus scrofaSwineDisinfectantsIodineAfrican swine fever viruscompound organic acidshighly complexed iodinesynergistic inactivation

Identifiers

PMID35588273
PMCPMC9195939
OpenAlexW4280577717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.