Evidence map›Paper›PMID 35588265›Full record

ArticleANZ journal of surgery2022

COVID-19 vaccine associated cervical lymphadenopathy: a case series.

Chelsea L Heaven, Lucy Barber, Omid Ahmadi, Kumanan Selvarajah, Subhaschandra Shetty

Open access · greenAbstract read
In one paragraph

Article in ANZ journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Chelsea L HeavenDepartment of Otolaryngology, Head & Neck Surgery, Whangarei Hospital, Whangarei, New Zealand.ORCID 0000-0002-4612-6085
Lucy BarberDepartment of Otolaryngology, Head & Neck Surgery, Whangarei Hospital, Whangarei, New Zealand.
Omid AhmadiFaculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Kumanan SelvarajahDepartment of Otolaryngology and Head & Neck Surgery, Waikato Hospital, Hamilton, New Zealand.
Subhaschandra ShettyDepartment of Otolaryngology, Head & Neck Surgery, Whangarei Hospital, Whangarei, New Zealand.
Northland District Health Board · NZUniversity of Auckland · NZWaikato Hospital · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 is an evolving worldwide pandemic causing significant morbidity and mortality. COVID-19 vaccinations have been developed to increase immunity against the virus. In New Zealand, the Pfizer BioNTech mRNA vaccine has been provisionally approved for use. Axillary lymphadenopathy is a recognized side effect of the mRNA vaccine, however cervical lymphadenopathy has also been reported. Due to a wide range of differential diagnoses, the finding of cervical lymphadenopathy requires thorough investigation which can include imaging and invasive diagnostic procedures.

methodsFive patients were identified by otorhinolaryngology (ORL) consultants at Whangarei Base Hospital and Waikato Hospital between 15/7/2021 and 21/12/2021 after being investigated through high suspicion of cancer triage pathways set by the New Zealand Ministry of Health. Inclusion criteria were adult patients with cervical lymphadenopathy following vaccination. Exclusion criteria were no history of vaccination or lymphadenopathy present before vaccination.

resultsAll patients were identified to have cervical lymphadenopathy on radiological imaging and a recent history of COVID-19 vaccination with the Pfizer BioNTech vaccine. Interval vaccination to fine needle aspiration time ranged between 41 and 76 days. All patients had cytological or histological diagnosis showing reactive findings or interval imaging showing resolution of lymphadenopathy.

conclusionWith increasing levels of COVID-19 vaccination and booster vaccinations we will continue to see cases of COVID-19 vaccine associated cervical lymphadenopathy. We highlight the importance of taking a COVID-19 vaccination history and including COVID-19 associated cervical lymphadenopathy in the differential diagnosis of presentation with a neck lump.

Indexed as

COVID-19COVID-19 VaccinesLymphadenopathyAdultHumansLymph NodesmRNA VaccinesVaccines, SyntheticCOVID-19 VaccinesmRNA VaccinesVaccines, Syntheticcervical lymphadenopathyCOVID-19 vaccine

Identifiers

PMID35588265
PMCPMC9348356
OpenAlexW4280496329

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.