ArticleAstrobiology2022
Catalytic Synthesis of Polyribonucleic Acid on Prebiotic Rock Glasses.
Article in Astrobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 65 citations in OpenAlex.
- Abiotic synthesis of RNase-resistant phosphodiester and pyrophosphate-linked polymers via thermodynamically controlled wet-dry cycling.Scientific reports · 2026Article
- Selection for growth drives the emergence of genetic heredity in protocells.PLoS biology · 2026Article
- Clay Minerals, Panacea or Parameter in RNA Oligomerization?Journal of molecular evolution · 2026Article
- A new LUCApedia database for data-driven research on early evolutionary history.Bioinformatics advances · 2026Article
- Interstep compatibility of a model for the prebiotic synthesis of RNA consistent with Hadean natural history.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Emergent Chemical Reactivity and Complexity of RNA Condensates.Angewandte Chemie (International ed. in English) · 2025Article
- Improving the Fidelity of Replication of a Six-Letter DNA Alphabet.ACS chemical biology · 2025Article
- Who Decides What Is Prebiotically Plausible? The Risks of Premature Constraints in Origin-of-Life Research.Life (Basel, Switzerland) · 2025Article
- A scope of prebiotic neat reaction conditions and the mechanism of urea-assisted phosphorylations of alcohols.Nature communications · 2025Article
- High-Yield Prebiotic Polymerization of 2',3'-Cyclic Nucleotides under Wet-Dry Cycling.ACS central science · 2025Article
- Polymerization and replication of primordial RNA induced by clay-water interface dynamics.Communications chemistry · 2025Article
- Assembly of catalytic complexes from randomized oligonucleotides.Science advances · 2025Article
- Origin of the RNA World in Cold Hadean Geothermal Fields Enriched in Zinc and Potassium: Abiogenesis as a Positive Fallout from the Moon-Forming Impact?Life (Basel, Switzerland) · 2025Article
- Cancer cell target discovery: comparing laboratory evolution of expanded DNA six-nucleotide alphabets with standard four-nucleotide alphabets.Nucleic acids research · 2025Article
- Do-Nothing Prebiotic Chemistry: Chemical Kinetics as a Window into Prebiotic Plausibility.Accounts of chemical research · 2025Article
- Dormancy in the origin, evolution and persistence of life on Earth.Proceedings. Biological sciences · 2025Review
- The HOMO-LUMO Gap as Discriminator of Biotic from Abiotic Chemistries.Life (Basel, Switzerland) · 2024Article
- On the Re-Creation of Protoribosome Analogues in the Lab.International journal of molecular sciences · 2024Review
- Microfluidics-Based Drying-Wetting Cycles to Investigate Phase Transitions of Small Molecules Solutions.Life (Basel, Switzerland) · 2024Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reported here are experiments that show that ribonucleoside triphosphates are converted to polyribonucleic acid when incubated with rock glasses similar to those likely present 4.3-4.4 billion years ago on the Hadean Earth surface, where they were formed by impacts and volcanism. This polyribonucleic acid averages 100-300 nucleotides in length, with a substantial fraction of 3',-5'-dinucleotide linkages. Chemical analyses, including classical methods that were used to prove the structure of natural RNA, establish a polyribonucleic acid structure for these products. The polyribonucleic acid accumulated and was stable for months, with a synthesis rate of 2 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.