ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2023
The risks associated with percutaneous native kidney biopsies: a prospective study.
Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Complication rates of 16- and 18-gauge needles for native kidney biopsies: a systematic review and proportional meta-analysis.Renal failure · 2026Pooled it
- Metabolome panels as potential noninvasive biomarkers for primary glomerulonephritis sub-types: meta-analysis of profiling metabolomics studies.Scientific reports · 2023Pooled it
- Lower eGFR is independently associated with embolization‑requiring severe bleeding after percutaneous renal biopsy: a matched case-control study with dose-respons e analysis.Renal failure · 2026Article
- From fundus to filtration: AI-driven retinal phenotyping as a framework for non-invasive prediction of kidney pathological categories (the "virtual renal biopsy" concept)- a narrative review.International urology and nephrology · 2026Review
- Predicting Major Bleeding in Native Kidney Biopsies: From External Validation of the Universal Bleeding Score to a New Clinical Tool.Journal of clinical medicine · 2026Article
- Review
- Urinary Exosomes as Potential Biomarkers for Diagnosis, Disease Activity Assessment, Treatment Monitoring, and Prognosis in Lupus Nephritis.International journal of molecular sciences · 2026Review
- Ten tips for kidney biopsy in cancer patients.Clinical kidney journal · 2026Review
- Safety and Effectiveness in 400 Image-Guided Spleen Biopsies from the DeGIR Registry.Cardiovascular and interventional radiology · 2026Article
- Percutaneous Kidney Biopsy: Indications, Technique, and Peri-Procedural Management-A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Acute left ovarian vein thrombosis following percutaneous renal biopsy: A case report.Radiology case reports · 2026Article
- Balancing Glomerular Adequacy and Bleeding Risk in Native Kidney Biopsy: A Multicenter Cohort Study of Multiple Needle Passes.Kidney medicine · 2026Article
- Volumetric MRI assessment of perirenal hematoma following biopsy of native and transplanted kidneys.International urology and nephrology · 2026Article
- Multiphase CT-based deep learning radiomics nomogram models for preoperative WHO/ISUP grading of clear cell renal cell carcinoma: a two-center validation study.BMC medical imaging · 2026Article
- Effectiveness and Safety of Image-Guided Renal Biopsies: Insights from 5,235 Procedures in the German Society for Interventional Radiology and Minimally Invasive Therapy (DeGIR) Registry.Cardiovascular and interventional radiology · 2026Article
- Personalized Nursing Approaches in Monitoring and Managing Hematoma Risks After Percutaneous Renal Biopsy: A Prospective Observational Study.Journal of nursing management · 2026Observational
- Charting new territory: outpatient stewardship in immunocompromised patients (first of a two-part series).Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Review
- Transitioning From Blind to Real-Time Ultrasound-Guided Kidney Biopsy in Children: Diagnostic Yield and Bleeding Outcomes in a Vietnamese Tertiary Referral Hospital, a Retrospective Cohort Study.International journal of nephrology · 2026Article
- Prognostic Factors for Complications Following Ultrasound-Guided Percutaneous Kidney Biopsy: A 7-Year Retrospective Study.Journal of clinical ultrasound : JCU · 2026Article
- From stethoscope to ultrasound: an Italian survey of nephrology ultrasound practice.Journal of nephrology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
43 authors at 20 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe known risks and benefits of native kidney biopsies are mainly based on the findings of retrospective studies. The aim of this multicentre prospective study was to evaluate the safety of percutaneous renal biopsies and quantify biopsy-related complication rates in Italy.
methodsThe study examined the results of native kidney biopsies performed in 54 Italian nephrology centres between 2012 and 2020. The primary outcome was the rate of major complications 1 day after the procedure, or for longer if it was necessary to evaluate the evolution of a complication. Centre and patient risk predictors were analysed using multivariate logistic regression.
resultsAnalysis of 5304 biopsies of patients with a median age of 53.2 years revealed 400 major complication events in 273 patients (5.1%): the most frequent was a ≥2 g/dL decrease in haemoglobin levels (2.2%), followed by macrohaematuria (1.2%), blood transfusion (1.1%), gross haematoma (0.9%), artero-venous fistula (0.7%), invasive intervention (0.5%), pain (0.5%), symptomatic hypotension (0.3%), a rapid increase in serum creatinine levels (0.1%) and death (0.02%). The risk factors for major complications were higher plasma creatinine levels [odds ratio (OR) 1.12 for each mg/dL increase, 95% confidence interval (95% CI) 1.08-1.17], liver disease (OR 2.27, 95% CI 1.21-4.25) and a higher number of needle passes (OR for each pass 1.22, 95% CI 1.07-1.39), whereas higher proteinuria levels (OR for each g/day increase 0.95, 95% CI 0.92-0.99) were protective.
conclusionsThis is the first multicentre prospective study showing that percutaneous native kidney biopsies are associated with a 5% risk of a major post-biopsy complication. Predictors of increased risk include higher plasma creatinine levels, liver disease and a higher number of needle passes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.