Evidence map›Paper›PMID 35587649›Full record

ArticleeLife2022

Kelsey Michelle Wells, Kai He, Aseem Pandey, Ana Cabello, Dongmei Zhang, Jing Yang, Gabriel Gomez, Yue Liu, Haowu Chang, Xueqiang Li and 17 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. BLOC1S1 Attenuates B. Melitensis 16M LPS-Triggered Autophagy by Spatial Confinement of TDP-43.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Beyond survival to domination:Frontiers in microbiology · 2025
    Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 4 institutions in 2 countries.

Kelsey Michelle WellsDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.ORCID 0000-0002-1657-5189
Kai HeDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, United States.ORCID 0000-0002-5805-3354
Aseem PandeyDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.
Ana CabelloDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.
Dongmei ZhangDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.
Jing YangDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.
Gabriel GomezTexas A&M Veterinary Medical Diagnostic Laboratory, Texas A&M University, College Station, United States.
Yue LiuCollege of Plant Sciences, Key Laboratory of Zoonosis Research, Ministry of Education, Jilin University, Jilin, China.ORCID 0000-0002-6213-5248
Haowu ChangKey Laboratory of Symbolic Computation and Knowledge Engineering, Ministry of Education, College of Computer Science and Technology, Jilin University, Changchun, China.
Xueqiang LiKey Laboratory of Symbolic Computation and Knowledge Engineering, Ministry of Education, College of Computer Science and Technology, Jilin University, Changchun, China.
Hao ZhangKey Laboratory of Symbolic Computation and Knowledge Engineering, Ministry of Education, College of Computer Science and Technology, Jilin University, Changchun, China.ORCID 0000-0002-2058-7123
Xuehuang FengDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.
Luciana Fachini da CostaDepartment of Veterinary Pathobiology, Texas A&M University, College Station, United States.
Richard MetzGenomics and Bioinformatics Services, Texas A&M University, College Station, United States.ORCID 0000-0002-9876-3385
Charles D JohnsonGenomics and Bioinformatics Services, Texas A&M University, College Station, United States.ORCID 0000-0003-3892-7082
Cameron Lee MartinDepartment of Poultry Science, Texas A&M University, College Station, United States.
Jill SkrobarczykDepartment of Poultry Science, Texas A&M University, College Station, United States.
Luc R BerghmanDepartment of Poultry Science, Texas A&M University, College Station, United States.
Kristin L PatrickDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.ORCID 0000-0003-2442-4679
Julian LeibowitzDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.ORCID 0000-0003-3485-3506
Allison FichtDepartment of Molecular and Cellular Medicine, College of Medicine, Texas A&M Health Science Center, College Station, United States.
Sing-Hoi SzeDepartment of Computer Science and Engineering, Dwight Look College of Engineering, Texas A&M University, College Station, United States.
Jianxun SongDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.
Xiaoning QianDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, United States.ORCID 0000-0002-4347-2476
Qing-Ming QinDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.ORCID 0000-0002-1723-6867
Thomas A FichtDepartment of Veterinary Pathobiology, Texas A&M University, College Station, United States.
Paul de FigueiredoDepartment of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Bryan, United States.ORCID 0000-0002-3878-5064
Texas A&M Health Science Center · USTexas A&M University · USJilin University · CNTexas A&M University System · US

Funding

Development of a High-Throughput Microfluidics-Enabled Functional Assay for Rapidly Identifying Neutralizing AntibodiesR01AI141607 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI DE FIGUEIREDO, PAUL, HAN, ARUM · 2019 to 2023
$3.4M
Improved Live Attenuated Brucella Vaccines to Reduce Human DiseasesR01HD084339 · NICHD · TEXAS A&M AGRILIFE RESEARCH · PI FICHT, THOMAS A · 2015 to 2017
$1.8M
Accelerating discovery of neutralizing paratopes with Functional Antibody Screening TechnologyR21AI139738 · NIAID · TEXAS A&M UNIVERSITY · PI HAN, ARUM · 2020 to 2021
$415k
MIRROR: A Chip-Scale Mid-IR Ring Resonance System for On-the-fly Reporting of AnalytesR21GM132705 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI HAN, ARUM · 2019 to 2020
$392k
NIAID NIH HHS R01 AI141607NIAID NIH HHS R21 AI139738NICHD NIH HHS R01 HD084339NIGMS NIH HHS R21 GM132705
6 · The paper itself

Abstract

The phagocytosis and destruction of pathogens in lysosomes constitute central elements of innate immune defense. Here, we show that

Indexed as

BrucellaBrucellosisAnimalsEndoribonucleasesEndosomesMiceProtein Serine-Threonine KinasesEndoribonucleasesProtein Serine-Threonine KinasesBLOS1BrucellaBrucella-containing vacuoles/lysosomes (BCVs)coronavirusinfectious diseaseintracellular parasitismmicrobiologymouseregulated IRE1α-dependent decay (RIDD)

Identifiers

PMID35587649
PMCPMC9119680
OpenAlexW4280539808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.