Evidence map›Paper›PMID 35587413›Full record

SynthesisJournal of psychopathology and clinical science2022

Posttraumatic stress disorder, drinking to cope, and harmful alcohol use: A multivariate meta-analysis of the self-medication hypothesis.

Matthew T Luciano, Samuel F Acuff, Cecilia C Olin, Rivian K Lewin, Justin C Strickland, Meghan E McDevitt-Murphy, James G Murphy

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in Journal of psychopathology and clinical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
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  14. Polygenic andmedRxiv : the preprint server for health sciences · 2025
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  18. Assessing shared psychological constructs as risk factors in comorbid PTSD-AUD combat-exposed male veterans.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Matthew T LucianoSan Diego State University Research Foundation.ORCID 0000-0003-4593-0001
Samuel F AcuffDepartment of Psychology.
Cecilia C OlinDepartment of Psychology.
Rivian K LewinDepartment of Psychology.ORCID 0000-0002-3789-9377
Justin C StricklandDepartment of Psychiatry and Behavioral Sciences.ORCID 0000-0003-1077-0394
Meghan E McDevitt-MurphyDepartment of Psychology.ORCID 0000-0002-3880-7083
James G MurphyDepartment of Psychology.
San Diego State University · US

Funding

HUMAN BEHAVIORAL PHARMACOLOGY OF SUBSTANCE ABUSET32DA007209 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Eric C. Strain, Elise M Weerts · 1985 to 2026
$12.9M
Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
Integration of Electrophysiological and Behavioral Economic Models of Reward Among Heavy Drinking Emerging AdultsF31AA027140 · NIAAA · UNIVERSITY OF MEMPHIS · PI ACUFF, SAMUEL FISHER · 2019 to 2021
$109k
Reducing hazardous drinking and PTSD-related avoidance through a brief alcohol intervention with an avoidance-focused feedback supplementF31AA026174 · NIAAA · UNIVERSITY OF MEMPHIS · PI LUCIANO, MATTHEW THOMAS · 2018 to 2018
$34k
NIAAA NIH HHS F31 AA026174NIAAA NIH HHS F31 AA027140NIAAA NIH HHS T32 AA013525NIDA NIH HHS T32 DA007209NIH HHS
6 · The paper itself

Abstract

The association between posttraumatic stress disorder (PTSD) and harmful alcohol use has often been explained through the self-medication hypothesis via coping-related drinking motives. However, the magnitude of the indirect effect of PTSD on harmful alcohol use through coping motives is unclear. This study aggregated this indirect effect using a meta-analytic structural equation modeling approach and explored moderators that influenced the indirect effect. We identified articles from PsycINFO, PubMed/MEDLINE, and PROQUEST (through June 22, 2021) containing measures of (a) PTSD symptoms, (b) coping-related drinking, and (c) harmful alcohol use. Thirty-four studies yielding 69 effect sizes were included (mean

Indexed as

AlcoholismStress Disorders, Post-TraumaticAdaptation, PsychologicalHumansMotivationSelf Medication

Identifiers

PMID35587413
PMCPMC9233097
OpenAlexW4280498944

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.