Evidence map›Paper›PMID 35587284›Full record

Trial reportInternational orthopaedics2022

Effect of joint immobilization using extension splint immediately after total knee arthroplasty on post-operative knee function and pain: a randomized clinical trial.

Mohammad Hasan Kaseb, Alireza Moharrami, Seyed Peyman Mirghaderi, Ehsan Fallah, Mohammadreza Razzaghof, Mir Mansour Moazen Jamshidi, Amirhossein Poopak, Seyed Mohammad Javad Mortazavi

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07552415 narecruitingnot on this mapstarted 2026, after this paper: background citation

Does Joint Immobilization Following Revision Total Knee Arthroplasty (rTKA) Improve Range of Motion Following Surgery?

TypeinterventionalSponsorHospital for Special Surgery, New YorkRan2026 to 2028Enrolled170ConditionsAseptic Revision Knee Arthroplasty, Stiffness Following Revision Knee ArthroplastyArmsKnee immobilizer, No Knee Immobilizer
NCT07690150 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Novel Angle: Manipulating Knee Position to Understand Muscle Deterioration During Leg Immobilization

TypeinterventionalSponsorWageningen UniversityRan2026 to 2028Enrolled30ConditionsMuscle Atrophy, Disuse Atrophy, ImmobilizationArmsKnee immobilization brace (0°) for 5 days, Knee immobilization brace (60°) for 5 days
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mohammad Hasan Kaseb *Joint Reconstruction Research Center, Tehran University Of Medical Sciences, Tehran, Iran.
Alireza Moharrami *Joint Reconstruction Research Center, Tehran University Of Medical Sciences, Tehran, Iran.
Seyed Peyman MirghaderiJoint Reconstruction Research Center, Tehran University Of Medical Sciences, Tehran, Iran.
Ehsan FallahJoint Reconstruction Research Center, Tehran University Of Medical Sciences, Tehran, Iran.
Mohammadreza RazzaghofJoint Reconstruction Research Center, Tehran University Of Medical Sciences, Tehran, Iran.
Mir Mansour Moazen JamshidiFellowship of Hip Surgery, Zanjan University of Medical Sciences, Tehran, Iran.
Amirhossein PoopakJoint Reconstruction Research Center, Tehran University Of Medical Sciences, Tehran, Iran.
Seyed Mohammad Javad MortazaviJoint Reconstruction Research Center, Tehran University Of Medical Sciences, Tehran, Iran. smjmort@yahoo.com.ORCID http://orcid.org/0000-0003-4189-7777
Tehran University of Medical Sciences · IRZanjan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInvestigate the effect of semirigid extension bracing after total knee arthroplasty (TKA) on articular pain and function.

methodsThe present randomized clinical trial included 72 patients undergoing unilateral primary TKA. Patients in the case group received eight days of post-operative semirigid extension-locked knee bracing, whereas controls did not. The outcomes assessed preoperatively and on the first, ninth, 30th day, and one year post-operatively included the knee society score (KSS), functional KSS (FKSS), VAS pain score, amount of postoperative opiate painkiller usage (tablet oxycodone 5mg), and knee ROM.

resultsThe case group had a significantly lower flexion ROM on postoperative day nine compared to the control group (95.3° vs. 100.8°, p=0.03), while it became significantly higher 1 month (114.1° vs. 104.7°, p=0.03) and one year post-operative (128.0° vs. 120.5°, p=0.002). Also, FKSS was significantly higher in the case group than in the controls in the one month post-operative assessment (37.0 vs. 32.6, p=0.009) but not in the one year post-operative assessment. The case group patients had a significantly lower pain than the controls on days one (5.8 vs. 7.2, p=0.02) and nine post-operative (4.1 vs. 5.2, p=0.048), but not at later assessments. The amount of one month post-operative opium (oxycodone) consumption was significantly lower in the brace group (12.4 vs. 14.1 tablets, p=0.03). The KSS were not significantly different between the groups after the surgery.

conclusionExtension-locked splinting immediately after TKA is a noninvasive, non-pharmacological, and inexpensive intervention with possible promising effects on knee ROM, short-term functional improvement, and acute post-operative pain management.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneeHumansKnee JointOxycodonePostoperative PainRange of Motion, ArticularSplintsTreatment OutcomeOxycodoneAcute painBraceImmobilizationKneeSplintsTotal knee arthroplasty

Identifiers

PMID35587284
OpenAlexW4280633161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.