ArticleHypertension (Dallas, Tex. : 1979)2022
Puberty Timing and Sex-Specific Trajectories of Systolic Blood Pressure: a Prospective Cohort Study.
Article in Hypertension (Dallas, Tex. : 1979), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Maternal obesity and offspring cardiovascular remodelling - the effect of preconception and antenatal lifestyle interventions: a systematic review.International journal of obesity (2005) · 2024Pooled it
- Increased fluid intake and blood pressure in healthy children: a randomized controlled trial. The SPA Project.Pediatric nephrology (Berlin, Germany) · 2026Trial
- Sustained effects of small-quantity lipid-based nutrient supplements provided during the first 1000 days on child growth at 9-11 y in a randomized controlled trial in Ghana.The American journal of clinical nutrition · 2024Trial
- Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause.Experimental physiology · 2026Review
- Endogenous and exogenous determinants of sex differences in blood pressure.NPJ cardiovascular health · 2026Review
- Influence of body mass index on blood pressure in children and adolescents: a cross-sectional school-based study.BMC public health · 2025Article
- Sex differences in metabolic syndrome among U.S. adolescents, NHANES 1999-2020.Diabetology & metabolic syndrome · 2025Article
- Intergenerational Socioeconomic Mobility and Cardiovascular Health Among Hispanic/Latino Youth and Caregivers Living in the United States.Journal of the American Heart Association · 2025Article
- Sex Hormone Androgen Elevates Blood Pressure Through Gut Microbiota-TMAO Pathway.Hypertension (Dallas, Tex. : 1979) · 2025Article
- Prediction of internalizing and externalizing symptoms in late childhood from attention-deficit/hyperactivity disorder symptoms in early childhood.Development and psychopathology · 2025Article
- Sex-specific socioeconomic inequalities in trajectories of anthropometry, blood pressure, and blood-based biomarkers from birth to 18 years: a prospective cohort study.European journal of public health · 2025Article
- Associations of central precocious puberty with blood pressure trajectories: prospective cohort study.Pediatric research · 2024Article
- Long-term changes in blood pressure and their health impact.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- The association between leisure-time physical activity and blood pressure changes from adolescence to young adulthood: Tehran Lipid and Glucose Study.Scientific reports · 2023Article
- Effects of Puberty on Blood Pressure Trajectories - Underlying Processes.Current hypertension reports · 2023Review
- Impact of puberty, sex determinants and chronic inflammation on cardiovascular risk in young people.Frontiers in cardiovascular medicine · 2023Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundSex differences in systolic blood pressure (SBP) emerge during adolescence but the role of puberty is not well understood. We examined sex-specific changes in SBP preceding and following puberty and examined the impact of puberty timing on SBP trajectories in females and males.
methodsTrajectories of SBP before and after puberty and by timing of puberty in females and males in a contemporary birth cohort study were analyzed. Repeated measures of height from age 5 to 20 years were used to identify puberty timing (age at peak height velocity). SBP was measured on ten occasions from 3 to 24 years (N participants, 4062; repeated SBP measures, 29 172). Analyses were performed using linear spline multilevel models based on time before and after puberty and were adjusted for parental factors and early childhood factors.
resultsMean age at peak height velocity was 11.7 years (SD, 0.8) for females and 13.6 years (SD, 0.9) for males. Males had faster rates of increase in SBP before puberty leading to 10.19 mm Hg (95% CI, 6.80-13.57) higher mean SBP at puberty which remained similar at 24 years (mean difference, 11.43 mm Hg [95% CI, 7.22-15.63]). Puberty timing was associated with small transient differences in SBP trajectories postpuberty in both sexes and small differences at 24 years in females only.
conclusionsA large proportion of the higher SBP observed in males compared with females in early adulthood is accrued before puberty. Interventions targeting puberty timing are unlikely to influence SBP in early adulthood.
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Registered trials
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