Evidence map›Paper›PMID 35586878›Full record

Trial reportActa neuropsychiatrica2022

Feasibility, acceptability and evaluation of meditation to augment yoga practice among persons diagnosed with schizophrenia.

Triptish Bhatia, Nupur Kumari, Ashok Yadav, Ram Pratap Beniwal, Gyandeepak Shah, Wood Joel, Jacquelynn R Jones, Satish Iyenger, Vishwajit L Nimgaonkar, Smita N Deshpande

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Acta neuropsychiatrica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Triptish BhatiaIndo-US Projects, Department of Psychiatry and De-addiction, Centre of Excellence in Mental Health, ABVIMS, Dr. Ram Manohar Lohia Hospital, New Delhi, India.ORCID https://orcid.org/0000-0003-0544-9707
Nupur KumariA multi-centric randomized controlled trial to evaluate the efficacy of telephone based psychological interventions on future suicide risk in suicide attempters, ICMR Project, Department of Psychiatry, Centre of Excellence in Mental Health, ABVIMS, Dr. Ram Manohar Lohia Hospital,New Delhi, India.
Ashok YadavA pilot project to evaluate efficacy of yoga intervention for stress, anxiety and depression among healthcare professionals working in a frontline COVID-19 tertiary care hospital of New Delhi, Department of Psychiatry and De-addiction, Centre of Excellence in Mental Health, ABVIMS, Dr. Ram Manohar Lohia Hospital,New Delhi, India.
Ram Pratap BeniwalDepartment of Psychiatry and De-addiction, Centre of Excellence in Mental Health, ABVIMS, Dr. Ram Manohar Lohia Hospital,New Delhi, India.
Gyandeepak ShahNational Coordination Unit-Indian Council of Medical Research, Dept. of Psychiatry and De-addiction, Centre of Excellence in Mental Health, ABVIMS, Dr. Ram Manohar Lohia Hospital,New Delhi, India.
Wood JoelDepartment of Psychiatry, WPIC, University of Pittsburgh, Pittsburgh, USA.
Jacquelynn R JonesDepartment of Psychiatry, WPIC, University of Pittsburgh, Pittsburgh, USA.
Satish IyengerDepartment of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Vishwajit L NimgaonkarDepartment of Psychiatry and Department of Human Genetics, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.
Smita N DeshpandeDepartment of Psychiatry, Centre of Excellence in Mental Health, Atal Bihari Vajpayee Institute of Medical Sciences-Dr. Ram Manohar Lohia Hospital, New Delhi, India.ORCID https://orcid.org/0000-0001-7770-9657

Funding

Psychiatric research infrastructure for intervention and implementation in India – TEAMSD43TW009114 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Smita N Deshpande, Mary Elizabeth Hawk · 2014 to 2026
$3.2M
The Impact of Yoga Supplementation On Cognitive Function Among Indian OutpatientsR01TW008289 · FIC · DR RAM MANOHAR LOHIA HOSPITAL · PI BHATIA, TRIPTISH · 2010 to 2014
$264k
FIC NIH HHS D43 TW009114FIC NIH HHS R01 TW008289
6 · The paper itself

Abstract

objectiveTo design a meditation protocol and test its feasibility, acceptability and efficacy in conjunction with yoga training (YT) for persons with schizophrenia (SZ).

methodsThe meditation protocol consisted of Anapana (observing normal respiration) and Yoga Nidra (supine, restful awareness). In a single-blind randomised controlled trial, medicated and clinically stable outpatients diagnosed with SZ were randomised to receive treatment as usual (TAU), TAU augmented with YT or TAU augmented with meditation and yoga training (MYT) for 3 weeks (N = 145). Acceptability, clinical, social and cognitive functions were assessed after 3-week and 3-month post-randomisation using within-group and between-group analyses with repeated measures multivariate tests.

resultsNo group-wise differences in compliance, study discontinuation, major/serious side effects or adverse events were noted. For six assessed clinical variables, the direction of changes were in the desired direction and the effect sizes were greater in the MYT group compared with the TAU group at both time points. Changes in social function variables were greater at 3 months than at 3 weeks. Nominally significant improvement in individual cognitive domains were noted in all groups at both time points. All effect sizes were in the small to medium range.

conclusionMYT is feasible and acceptable and shows modest benefits for persons with SZ. MYT can also improve quality of life and clinical symptoms. Larger studies of longer duration are warranted.

Indexed as

MeditationSchizophreniaYogaFeasibility StudiesHumansQuality of LifeSingle-Blind Methodcognitionmeditationrandomised controlled trialschizophreniayoga

Identifiers

PMID35586878
PMCPMC10174753

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.