Evidence map›Paper›PMID 35586748›Full record

ArticleGlobal heart2022

Serum Atrial Natriuretic Peptide,

Linan Chen, Jing Li, Min Zhang, Qiu Zhang, Lei Wu, Ying Lu, Yan He, Jun Jiang, Xiaolong Zhang, Jianwei Hu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Global heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Linan ChenDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.ORCID 0000-0002-4926-0191
Jing LiDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.ORCID 0000-0001-9591-8858
Min ZhangDepartment of Central Office, Suzhou National New and Hi-tech Industrial Development Zone Center for Disease Control and Prevention, Suzhou, China.
Qiu ZhangDepartment of Chronic Disease, Gusu Center for Disease Control and Prevention, Suzhou, China.
Lei WuDepartment of Maternal and Child Health, Suzhou Industrial Park Center for Disease Control and Prevention, Suzhou, China.
Ying LuDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Yan HeDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Jun JiangDepartment of Tuberculosis Control, Suzhou Center for Disease Control and Prevention, Suzhou, China.
Xiaolong ZhangDepartment of Tuberculosis Control, Suzhou Center for Disease Control and Prevention, Suzhou, China.
Jianwei HuDepartment of Central Office, Maternal and Child Health Bureau of Kunshan, Suzhou, China.
Yi DingDepartment of Preventive Medicine, College of Clinical Medicine, Suzhou Vocational Health College, Suzhou, China.
Mingzhi ZhangDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Hao PengDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.ORCID 0000-0001-6277-662X
Soochow University · CNTaiwan Centers for Disease Control · TWChinese Center For Disease Control and Prevention · CNSuzhou Vocational Health College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial natriuretic peptide (ANP) has been associated with cardiovascular disease (CVD) and related risk factors, but the clinical application is limited and the underlying mechanisms are not very clear. Here, we aimed to examine whether proANP and its coding gene methylation were associated with CVD in the Chinese population. Methods: Serum proANP and peripheral blood DNA methylation of natriuretic peptide A gene ( Results: During follow-up, 210 participants developed CVD events, 50 participants died from non-cardiovascular causes, and 214 participants were lost. Per 1-nmol/L increment of serum proANP was associated with a 22% (HR = 1.22, 95%CI: 1.03-1.44, Conclusions: Increased proANP and hypomethylation at

Indexed as

Atrial Natriuretic FactorCardiovascular DiseasesAdultBiomarkersChinaDNA MethylationFemaleFollow-Up StudiesHumansMaleMiddle AgedNatriuretic PeptidesProcainamidePromoter Regions, GeneticAtrial Natriuretic FactorBiomarkersNatriuretic PeptidesNPPA protein, humanProcainamideatrial natriuretic peptidecardiovascular diseaseDNA methylationprospective cohort study

Identifiers

PMID35586748
PMCPMC8992767
OpenAlexW4225738458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.