Evidence map›Paper›PMID 35586596›Full record

ArticleJournal of ophthalmology2022

Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap Transplantation.

Po-Yen Lee, Yo-Chen Chang, Pei-Kang Liu, Tzu-En Kao, Horng-Jiun Wu, Kuo-Jen Chen, Kwou-Yeung Wu, Kai-Chun Cheng, Wen-Chuan Wu

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Optimal approaches for managing recurrent macular holes: a comprehensive systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Po-Yen LeeDepartment of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.
Yo-Chen ChangDepartment of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.ORCID https://orcid.org/0000-0001-8751-3148
Pei-Kang LiuDepartment of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.ORCID https://orcid.org/0000-0002-6417-4363
Tzu-En KaoDepartment of Ophthalmology, Park One International Hospital, Kaohsiung 81357, Taiwan.
Horng-Jiun WuDepartment of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.
Kuo-Jen ChenDepartment of Ophthalmology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, Kaohsiung 81267, Taiwan.ORCID https://orcid.org/0000-0003-0733-5017
Kwou-Yeung WuDepartment of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.
Kai-Chun ChengDepartment of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.ORCID https://orcid.org/0000-0002-1240-4219
Wen-Chuan WuDepartment of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.ORCID https://orcid.org/0000-0001-5930-834X
Kaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the long-term anatomic and functional outcomes of autologous neurosensory retinal free flap transplantation (ART) for patients with refractory large macular hole (MH). Design: Retrospective interventional case series. Methods: We reviewed 9 patients who underwent ART for their refractory large MH. In this extended follow-up study, postoperative assessment including spectral-domain optical coherence tomography and best-corrected visual acuity (BCVA) were recorded at 12, 15, 18, 21, and 24 months after surgery. Results: The macular hole of all patients appeared successfully closed during the whole follow-up period. The mean logMAR BCVA improved from 1.61 ± 0.44 (preoperative) to 0.72 ± 0.30 (12 months after surgery) ( Conclusion: ART is a good alternative technique for closing large refractory macular holes. Although inner retinal cystic changes were observed in 4 eyes (44.4%), this phenomenon did not significantly affect visual acuity. It provides long-term good anatomical and functional results, especially in cases where insufficient ILM or lens capsule are left.

Identifiers

PMID35586596
PMCPMC9110223
OpenAlexW4229443468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.