Evidence map›Paper›PMID 35586528›Full record

ArticleMovement disorders clinical practice2022

Diagnostic Neurophysiologic Biomarkers for Task-Specific Dystonia.

Shabbir Hussain I Merchant, Tianxia Wu, Mark Hallett

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Movement disorders clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Somato-Cognitive Action Network in Focal Dystonia.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shabbir Hussain I MerchantDepartment of Neurology, Division of Movement Disorders, Harvard Medical School Beth Israel Deaconess Medical Center Boston Massachusetts USA.ORCID https://orcid.org/0000-0002-1718-3961
Tianxia WuNational Institute of Neurological Disorders and Stroke National Institute of Health Bethesda Maryland USA.
Mark HallettNational Institute of Neurological Disorders and Stroke National Institute of Health Bethesda Maryland USA.ORCID https://orcid.org/0000-0002-3180-6811
National Institute of Neurological Disorders and Stroke · USBeth Israel Deaconess Medical Center · US

Funding

Pathophysiology of Basal Ganglia DisordersZIANS003031 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI HALLETT, MARK · 2009 to 2023
$22.7M
6 · The paper itself

Abstract

Background: Task-specific dystonia (TSD) is a challenging clinical diagnosis with no objective diagnostic biomarkers. Objective: The objective of this study was to test 2 neurophysiologic variables using transcranial magnetic stimulation as potential diagnostic biomarkers for TSD. Methods: We tested (1) cortical silent period (CSP) and (2) dorsal inferior parietal lobule-motor cortex (dIPL-M1) physiologic connectivity in 9 patients with the writer's cramp form of TSD and 12 healthy volunteers on 2 separate sessions. Results: CSP was significantly prolonged ( Conclusion: CSP and dIPL-M1 physiologic connectivity can classify TSD with high sensitivity, specificity, reproducibility, and reliability.

Indexed as

cortical silent perioddiagnostic biomarkersdystoniatask‐specific dystoniatranscranial magnetic stimulation

Identifiers

PMID35586528
PMCPMC9092748
OpenAlexW4223957606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.