Evidence map›Paper›PMID 35586448›Full record

ArticleERJ open research2022

Noninvasive diagnosis of pulmonary hypertension with hyperpolarised

Elianna A Bier, Fawaz Alenezi, Junlan Lu, Ziyi Wang, Joseph G Mammarappallil, Bryan O'Sullivan-Murphy, Alaattin Erkanli, Bastiaan Driehuys, Sudarshan Rajagopal

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 21 citations in OpenAlex.

  1. Correlating Pulmonary Hemodynamics With HPMagnetic resonance in medicine · 2026
    Article
  2. Article
  3. Article
  4. Dynamic RBC-To-Membrane Ratio inMagnetic resonance in medicine · 2026
    Article
  5. The emerging role of hyperpolarizedExpert review of respiratory medicine · 2025
    Article
  6. Article
  7. Article
  8. Functional Pulmonary Imaging.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  9. Review
  10. Review
  11. Combining hyperpolarizedJournal of applied physiology (Bethesda, Md. : 1985) · 2025
    Article
  12. Article
  13. Mapping the amplitude and phase of dissolvedMagnetic resonance in medicine · 2025
    Article
  14. Article
  15. Review
  16. HyperpolarizedJHLT open · 2024
    Article
  17. Article
  18. Functional gas exchange measures onFrontiers in medicine · 2024
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Elianna A BierDept of Biomedical Engineering, Duke University, Durham, NC, USA.ORCID https://orcid.org/0000-0002-2313-3450
Fawaz AleneziDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Junlan LuMedical Physics Graduate Program, Duke University, Durham, NC, USA.
Ziyi WangDept of Biomedical Engineering, Duke University, Durham, NC, USA.
Joseph G MammarappallilDept of Radiology, Duke University Medical Center, Durham, NC, USA.
Bryan O'Sullivan-MurphyDept of Radiology, Duke University Medical Center, Durham, NC, USA.
Alaattin ErkanliDept of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA.
Bastiaan DriehuysDept of Radiology, Duke University Medical Center, Durham, NC, USA.
Sudarshan RajagopalDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Duke Medical Center · USDuke University · US

Funding

Early Detection of Changes in Pulmonary Gas Exchange by Hyperpolarized Xe MRIR01HL105643 · NHLBI · DUKE UNIVERSITY · PI Bastiaan Driehuys · 2011 to 2026
$6.7M
Using MRI To Visualize Regional Therapy Response In Idiopathic Pulmonary FibrosisR01HL126771 · NHLBI · DUKE UNIVERSITY · PI Bastiaan Driehuys · 2015 to 2026
$6.6M
NHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS R01 HL105643NHLBI NIH HHS R01 HL126771
6 · The paper itself

Abstract

Background: The diagnosis of pulmonary hypertension (PH) remains challenging. Pre- and post-capillary PH have different signatures on noninvasive Methods: Results: For pre-capillary PH, Conclusion: This study demonstrates the potential to develop

Identifiers

PMID35586448
PMCPMC9108963
OpenAlexW4225647641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.