Evidence map›Paper›PMID 35586253›Full record

ArticleFrontiers in cellular and infection microbiology2022

Combined Microbiome and Metabolome Analysis Reveals a Novel Interplay Between Intestinal Flora and Serum Metabolites in Lung Cancer.

Sai Chen, Rong Gui, Xiong-Hui Zhou, Jun-Hua Zhang, Hai-Ye Jiang, Hai-Ting Liu, Yun-Feng Fu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sai ChenDepartment of Blood Transfusion, The Third Xiangya Hospital of Central South University, Changsha, China.
Rong GuiDepartment of Blood Transfusion, The Third Xiangya Hospital of Central South University, Changsha, China.
Xiong-Hui ZhouDepartment of Blood Transfusion, The Third Xiangya Hospital of Central South University, Changsha, China.
Jun-Hua ZhangDepartment of Blood Transfusion, The Third Xiangya Hospital of Central South University, Changsha, China.
Hai-Ye JiangDepartment of Laboratory Medicine, The Third Xiangya Hospital of Central South University, Changsha, China.
Hai-Ting LiuDepartment of Blood Transfusion, The Third Xiangya Hospital of Central South University, Changsha, China.
Yun-Feng FuDepartment of Blood Transfusion, The Third Xiangya Hospital of Central South University, Changsha, China.
Central South University · CNThird Xiangya Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the leading cause of cancer death, lung cancer seriously endangers human health and quality of life. Although many studies have reported the intestinal microbial composition of lung cancer, little is known about the interplay between intestinal microbiome and metabolites and how they affect the development of lung cancer. Herein, we combined 16S ribosomal RNA (rRNA) gene sequencing and liquid chromatography-mass spectrometry (LC-MS) technology to analyze intestinal microbiota composition and serum metabolism profile in a cohort of 30 lung cancer patients with different stages and 15 healthy individuals. Compared with healthy people, we found that the structure of intestinal microbiota in lung cancer patients had changed significantly (Adonis,

Indexed as

Gastrointestinal MicrobiomeLung NeoplasmsFecesHumansMetabolomeQuality of LifeRNA, Ribosomal, 16SValineRNA, Ribosomal, 16SValinebiomarkerintestinal floraintestinal microorganismlung cancerserum metabolites

Identifiers

PMID35586253
PMCPMC9108287
OpenAlexW4225264529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.