ArticleFrontiers in medicine2022
Epidemiological, Clinical, and Trichoscopic Features of Syphilitic Alopecia: A Retrospective Analysis and Systematic Review.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Platelet-rich plasma in alopecia areata and primary cicatricial alopecias: A systematic review.Frontiers in medicine · 2022Pooled it
- Case Report: Secondary syphilitic alopecia following non-penetrative sexual contact: a case of initial misdiagnosis.Frontiers in medicine · 2026Article
- Clinical and trichoscopic features of early congenital syphilis: a single-center cross-sectional study.Frontiers in medicine · 2026Article
- A Three-Step Diagnostic Algorithm for Alopecia: Pattern Analysis in Trichoscopy.Journal of clinical medicine · 2025Article
- Alopecia as the initial presentation of secondary syphilis: A case report and review of literature.IDCases · 2025Article
- Southern African HIV Clinicians Society Guideline for the clinical management of syphilis.Southern African journal of HIV medicine · 2024Article
- Beard Alopecia: An Updated and Comprehensive Review of Etiologies, Presentation and Treatment.Journal of clinical medicine · 2023Review
- SARS-CoV-2 Infection-A Trigger Factor for Telogen Effluvium: Review of the Literature with a Case-Based Guidance for Clinical Evaluation.Life (Basel, Switzerland) · 2023Review
- Trichoscopic Features of Syphilitic Alopecia and Alopecia Areata: A Comparative Study.Clinical, cosmetic and investigational dermatology · 2023Article
- Moth-eaten alopecia and beyond: Syphilitic alopecia - Revisited.Indian journal of sexually transmitted diseases and AIDSArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Syphilitic alopecia (SA), which mimics other types of alopecia, is an uncommon manifestation of secondary syphilis. Trichoscopic features may facilitate its diagnosis. However, studies on SA and its trichoscopic characteristics remain limited. Objective: To investigate the epidemiological, clinical, and trichoscopic findings and laboratory results, treatment, and outcomes of SA in Thai patients as well as to comprehensively summarize all trichoscopic features of SA through a systematic review. Methods: Data on patients diagnosed with SA between December 2010 and December 2021 were obtained from their medical records and analyzed retrospectively. A systematic review of trichoscopic data, both from our institution and from studies registered in the PubMed, MEDLINE, and Embase databases, was conducted. A descriptive summarization was performed to comprehensively study the trichoscopic features of SA. Results: Of the 205 patients with secondary syphilis, 23 patients with SA (symptomatic SA: 20, essential SA: 3) were included. The mean age was 27.6 ± 8.8 years, and male predominance was noted. The moth-eaten pattern was the most common SA presentation, and the parieto-occipital scalp was the most commonly affected area. All patients with SA achieved significant hair regrowth within 3 months of antibiotic therapy. Trichoscopic images were available for 20 patients with SA from our institute and were included in the systematic review. Fourteen articles provided information on 21 patients. Overall ( Conclusions: Given the progressively increasing frequency of SA, trichoscopic examination may be valuable when SA is suspected in patients with idiopathic alopecia; however, our findings are quite non-specific. The absence of exclamation mark hairs may help in the diagnosis of SA. Further comparative studies on other types of alopecia are required to determine the most useful diagnostic features.
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