Evidence map›Paper›PMID 35586063›Full record

ArticleFrontiers in pharmacology2022

The Bradycardic Agent Ivabradine Acts as an Atypical Inhibitor of Voltage-Gated Sodium Channels.

Benjamin Hackl, Peter Lukacs, Janine Ebner, Krisztina Pesti, Nicholas Haechl, Mátyás C Földi, Elena Lilliu, Klaus Schicker, Helmut Kubista, Anna Stary-Weinzinger and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Ligand-based pharmacophore modeling for the discovery of NaJournal of computer-aided molecular design · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Benjamin HacklDepartment of Neurophysiology and Neuropharmacology, Medical University of Vienna, Vienna, Austria.
Peter LukacsELKH, Plant Protection Institute, Centre for Agricultural Research, Martonvásár, Hungary.
Janine EbnerDepartment of Neurophysiology and Neuropharmacology, Medical University of Vienna, Vienna, Austria.
Krisztina PestiDepartment of Biochemistry, ELTE Eötvös Loránd University, Budapest, Hungary.
Nicholas HaechlDepartment of Neurophysiology and Neuropharmacology, Medical University of Vienna, Vienna, Austria.
Mátyás C FöldiELKH, Plant Protection Institute, Centre for Agricultural Research, Martonvásár, Hungary.
Elena LilliuDepartment of Neurophysiology and Neuropharmacology, Medical University of Vienna, Vienna, Austria.
Klaus SchickerDepartment of Neurophysiology and Neuropharmacology, Medical University of Vienna, Vienna, Austria.
Helmut KubistaDepartment of Neurophysiology and Neuropharmacology, Medical University of Vienna, Vienna, Austria.
Anna Stary-WeinzingerDepartment of Pharmacology and Toxicology, University of Vienna, Vienna, Austria.
Karlheinz HilberDepartment of Neurophysiology and Neuropharmacology, Medical University of Vienna, Vienna, Austria.
Arpad MikeELKH, Plant Protection Institute, Centre for Agricultural Research, Martonvásár, Hungary.
Hannes TodtDepartment of Neurophysiology and Neuropharmacology, Medical University of Vienna, Vienna, Austria.
Xaver KoenigDepartment of Neurophysiology and Neuropharmacology, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATEötvös Loránd University · HUCentre for Agricultural Research · HUPlant Protection Institute · HUUniversity of Vienna · AT

Funding

Austrian Science Fund FWF I 4649Austrian Science Fund FWF P 30234Austrian Science Fund FWF P 31563
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

atypical inhibitorconduction cellivabradineS16257ventricular cardiomyocytevoltage-gated sodium channel

Identifiers

PMID35586063
PMCPMC9108390
OpenAlexW4225277477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.