Evidence map›Paper›PMID 35586043›Full record

ArticleFrontiers in pharmacology2022

Tag-SNPs in Phospholipase-Related Genes Modify the Susceptibility to Nephrosclerosis and its Associated Cardiovascular Risk.

Luz M González, Nicolás R Robles, Sonia Mota-Zamorano, José C Arévalo-Lorido, José Manuel Valdivielso, Juan López-Gómez, Guillermo Gervasini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Link between mutations inWorld journal of gastrointestinal surgery · 2024
    Article
  2. The Link between Prostanoids and Cardiovascular Diseases.International journal of molecular sciences · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Luz M GonzálezDepartment of Medical and Surgical Therapeutics, Medical School, Institute of Molecular Pathology Biomarkers, University of Extremadura, Badajoz, Spain.
Nicolás R RoblesService of Nephrology, Badajoz University Hospital, Badajoz, Spain.
Sonia Mota-ZamoranoDepartment of Medical and Surgical Therapeutics, Medical School, Institute of Molecular Pathology Biomarkers, University of Extremadura, Badajoz, Spain.
José C Arévalo-LoridoService of Internal Medicine, Badajoz University Hospital, Badajoz, Spain.
José Manuel ValdivielsoVascular and Renal Translational Research Group, UDETMA, IRBLleida, Lleida, Spain.
Juan López-GómezService of Clinical Analyses, Badajoz University Hospital, Badajoz, Spain.
Guillermo GervasiniDepartment of Medical and Surgical Therapeutics, Medical School, Institute of Molecular Pathology Biomarkers, University of Extremadura, Badajoz, Spain.
Universidad de Extremadura · ESCentro de Implantología Cirugía Oral y Maxilofacial · ESBiomedical Research Institute of Lleida · ESSpanish Clinical Research Network · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nephrosclerosis patients have a high cardiovascular (CV) risk that is very often of more concern than the renal disease itself. We aimed to determine whether variants in phospholipase-related genes, associated with atherosclerosis and CV outcomes in the general population, could constitute biomarkers of nephrosclerosis and/or its associated CV risk. We screened 1,209 nephrosclerosis patients and controls for 86 tag-SNPs that were identified in the

Indexed as

atherosclerosiscardiovascular risknephrosclerosisphospholipasessingle nucleotide polymorphism

Identifiers

PMID35586043
PMCPMC9108153
OpenAlexW4225290323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.