Evidence map›Paper›PMID 35585921›Full record

ArticleFrontiers in neuroscience2022

Dietary Supplementation With

Yuhuan Xue, Xiaoyan Zhu, Wenyong Yan, Zhihan Zhang, Enhui Cui, Yongji Wu, Cixia Li, Jiarong Pan, Qijiang Yan, Xuejun Chai and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Frontiers in nutrition · 2026
    Article
  3. Fisetin Mitigates Ferroptosis and Promotes Remyelination in a Cuprizone Model of Multiple Sclerosis.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Remyelination in Multiple Sclerosis: Findings in the Cuprizone Model.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Yuhuan XueCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Xiaoyan ZhuCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Wenyong YanCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Zhihan ZhangCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Enhui CuiCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Yongji WuCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Cixia LiCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Jiarong PanCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Qijiang YanMultiple Sclerosis Research Center of New York, New York, NY, United States.
Xuejun ChaiDepartment of Basic Medicine, Xi'an Medical University, Xi'an, China.
Shanting ZhaoCollege of Veterinary Medicine, Northwest A&F University, Yangling, China.
Northwest A&F University · CNMultiple Sclerosis Center Of Northeastern New York · USXi'an Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Multiple sclerosis is a chronic demyelinating disease of uncertain etiology. Traditional treatment methods produce more adverse effects. Epidemiological and clinical treatment findings showed that unknown environmental factors contribute to the etiology of MS and that diet is a commonly assumed factor. Despite the huge interest in diet expressed by people with MS and the potential role diet plays in MS, very little data is available on the role of diet in MS pathogenesis and MS course, in particular, studies on fats and MS. The oil of Objective: Here, we investigated the underlying influences of Methods: Cuprizone (0.2% in chow) was used to establish a mouse model of demyelination. Results: Mice exposed to cuprizone for 6 weeks showed schizophrenia-like behavioral changes, the increased exploration of the center in the open field test (OFT), increased entries into the open arms of the elevated plus-maze, as well as demyelination in the corpus callosum. After cuprizone withdrawal, the diet therapy was initiated with supplementation of Conclusion: Diet supplementation with

Indexed as

Acer truncatum oilcuprizonedemyelinationneurodegenerative diseaseremyelination

Identifiers

PMID35585921
PMCPMC9109879
OpenAlexW4225275132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.