Evidence map›Paper›PMID 35585881›Full record

ArticleOxidative medicine and cellular longevity2022

Fetal Zone Steroids Show Discrete Effects on Hyperoxia-Induced Attenuation of Migration in Cultured Oligodendrocyte Progenitor Cells.

Donna E Sunny, Elisabeth L Krüger, Elke Hammer, Uwe Völker, Matthias Heckmann

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Donna E SunnyDepartment of Neonatology and Pediatric Intensive Care, University Medicine Greifswald, Greifswald 17475, Germany.ORCID https://orcid.org/0000-0001-5595-5363
Elisabeth L KrügerDepartment of Neonatology and Pediatric Intensive Care, University Medicine Greifswald, Greifswald 17475, Germany.
Elke HammerDepartment of Functional Genomics, University Medicine Greifswald, Greifswald 17475, Germany.ORCID https://orcid.org/0000-0002-1507-0402
Uwe VölkerDepartment of Functional Genomics, University Medicine Greifswald, Greifswald 17475, Germany.ORCID https://orcid.org/0000-0002-5689-3448
Matthias HeckmannDepartment of Neonatology and Pediatric Intensive Care, University Medicine Greifswald, Greifswald 17475, Germany.ORCID https://orcid.org/0000-0002-5260-264X
Universitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral oxygenation disturbances contribute to the pathogenesis of brain lesions in preterm infants with white matter damage. These children are at risk of developing long-term neurodevelopmental disabilities. Preterm birth is associated with sudden hormonal changes along with an untimely increase in oxygen tissue tension. There is a persistent high postnatal production of fetal zone steroids (FZS), which serve in the fetoplacental unit as precursors for placental estrogen synthesis during pregnancy. The role of FZS in events associated with oxygenation differences and their impact on the developing white matter is not well understood. Therefore, we investigated the effect of hyperoxia (80% O

Indexed as

HyperoxiaOligodendrocyte Precursor CellsPremature BirthAnimalsDehydroepiandrosteroneEstradiolFemaleHumansInfant, NewbornInfant, PrematurePlacentaPregnancyProteomicsRatsSteroidsDehydroepiandrosteroneEstradiolSteroids

Identifiers

PMID35585881
PMCPMC9110221
OpenAlexW4229457845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.