Evidence map›Paper›PMID 35585633›Full record

SynthesisHealth and quality of life outcomes2022

Predictors of health-related quality of life after cardiac surgery: a systematic review.

Julie Sanders, Tracey Bowden, Nicholas Woolfe-Loftus, Mandeep Sekhon, Leanne M Aitken

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Health and quality of life outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Quality of Life After Cardiac Surgery: The QUACS Study and Benefit Prediction Model.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julie SandersSt Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, EC1A 7DN, UK. j.sanders@qmul.ac.uk.
Tracey BowdenSchool of Health Sciences, City, University of London, London, EC1V 0HB, UK.
Nicholas Woolfe-LoftusSt Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, EC1A 7DN, UK.
Mandeep SekhonSchool of Health Sciences, City, University of London, London, EC1V 0HB, UK.
Leanne M AitkenSchool of Health Sciences, City, University of London, London, EC1V 0HB, UK.

Funding

Barts Charity MRD0181
6 · The paper itself

Abstract

backgroundHealth-related quality of life (HRQoL) is important in determining surgical success, particularly from the patients' perspective.

aimsTo identify predictors for HRQoL outcome after cardiac surgery in order to identify potentially modifiable factors where interventions to improve patient outcomes could be targeted.

methodsElectronic databases (including MEDLINE, CINAHL, Embase) were searched between January 2001 and December 2020 for studies determining predictors of HRQoL (using a recognised and validated tool) in adult patients undergoing cardiac surgery. Data extraction and quality assessments were undertaken and data was summarised using descriptive statistics and narrative synthesis, as appropriate.

resultsOverall, 3924 papers were screened with 41 papers included in the review. Considerable methodological heterogeneity between studies was observed. Most were single-centre (75.6%) prospective observational studies (73.2%) conducted in patients undergoing coronary artery bypass graft (CABG) (n = 51.2%) using a version of the SF-36 (n = 63.4%). Overall, 103 independent predictors (62 pre-operative, five intra-operative and 36 post-operative) were identified, where 34 (33.0%) were reported in more than one study. Potential pre-operative modifiable predictors include alcohol use, BMI/weight, depression, pre-operative quality of life and smoking while in the post-operative period pain and strategies to reduce post-operative complications and intensive care and hospital length of stay are potential therapeutic targets.

conclusionDespite a lack of consistency across studies, several potentially modifiable predictors were identified that could be targeted in interventions to improve patient or treatment outcomes. This may contribute to delivering more person-centred care involving shared decision-making to improve patient HRQoL after cardiac surgery.

Indexed as

Cardiac Surgical ProceduresQuality of LifeAdultCoronary Artery BypassHumansObservational Studies as TopicPostoperative PeriodProspective StudiesCardiac surgeryHealth-related quality of livePatient reported outcomePredictorsQuality of life

Identifiers

PMID35585633
PMCPMC9118761

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.