Evidence map›Paper›PMID 35585575›Full record

ArticleBMC public health2022

The impact of COVID-19 vaccination in prisons in England and Wales: a metapopulation model.

Ciara V McCarthy, Oscar O'Mara, Edwin van Leeuwen, CMMID COVID-19 Working Group, Mark Jit, Frank Sandmann

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. COVID-19-Infections and Immunization of Inmates in Penitentiary Institutions in Poland in 2021.International journal of environmental research and public health · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ciara V McCarthyCentre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK. Ciara.McCarthy1@lshtm.ac.uk.
Oscar O'MaraHer Majesty's Prison and Probation Service, London, UK & the University of Nottingham, Nottingham, UK.
Edwin van LeeuwenCentre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK.
CMMID COVID-19 Working Group
Mark Jit *Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Frank Sandmann *Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK.
London School of Hygiene & Tropical Medicine · GBUniversity of Nottingham · GB

Funding

Does repeated influenza vaccination constrain influenza immune responses and protection?R01AI141534 · NIAID · UNIVERSITY OF MELBOURNE · PI FOX, ANNETTE, KUCHARSKI, ADAM JAMES · 2019 to 2023
$4.9M
Medical Research Council MC_PC_19065Medical Research Council MR/V027956/1NIAID NIH HHS R01 AI141534Wellcome Trust 208812/Z/17/ZWellcome Trust 210758/Z/18/Z
6 · The paper itself

Abstract

backgroundHigh incidence of cases and deaths due to coronavirus disease 2019 (COVID-19) have been reported in prisons worldwide. This study aimed to evaluate the impact of different COVID-19 vaccination strategies in epidemiologically semi-enclosed settings such as prisons, where staff interact regularly with those incarcerated and the wider community.

methodsWe used a metapopulation transmission-dynamic model of a local prison in England and Wales. Two-dose vaccination strategies included no vaccination, vaccination of all individuals who are incarcerated and/or staff, and an age-based approach. Outcomes were quantified in terms of COVID-19-related symptomatic cases, losses in quality-adjusted life-years (QALYs), and deaths.

resultsCompared to no vaccination, vaccinating all people living and working in prison reduced cases, QALY loss and deaths over a one-year period by 41%, 32% and 36% respectively. However, if vaccine introduction was delayed until the start of an outbreak, the impact was negligible. Vaccinating individuals who are incarcerated and staff over 50 years old averted one death for every 104 vaccination courses administered. All-staff-only strategies reduced cases by up to 5%. Increasing coverage from 30 to 90% among those who are incarcerated reduced cases by around 30 percentage points.

conclusionsThe impact of vaccination in prison settings was highly dependent on early and rapid vaccine delivery. If administered to both those living and working in prison prior to an outbreak occurring, vaccines could substantially reduce COVID-19-related morbidity and mortality in prison settings.

Indexed as

COVID-19PrisonsCOVID-19 VaccinesEnglandHumansMiddle AgedSARS-CoV-2VaccinationWalesCOVID-19 VaccinesCOVID-19Mathematical modelPrisonsPublic healthVaccination

Identifiers

PMID35585575
PMCPMC9115545
OpenAlexW4280548519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.