Evidence map›Paper›PMID 35585514›Full record

ArticleBMC pregnancy and childbirth2022

Clinical analysis of 2860 cases of diabetes in pregnancy: a single-center retrospective study.

Jia Chen, Zhenyu Wang, Weizhen Wu, Haixia Chen, Caijuan Zhong, Lixuan Liang, Yingtao Li

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jia Chen *Department of Obstetrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Zhenyu Wang *Department of Obstetrics and Gynecology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, 510120, China.
Weizhen WuDepartment of Obstetrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Haixia ChenDepartment of Obstetrics, Foshan Women and Children hospital, Foshan, 528000, China.
Caijuan ZhongDepartment of Obstetrics, Guangdong Women and Children Hospital, Guangzhou, 510010, China.
Lixuan LiangDepartment of Obstetrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Yingtao LiDepartment of Obstetrics, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China. Yingtao9777@163.com.
Guangzhou Medical University · CNFoshan Maternity and Child Health Care Hospital · CNGuangdong Province Women and Children Hospital · CNSun Yat-sen University · CN

Funding

Basic and Applied Basic Research Fund Project of Guangdong Province 2020A1515011347University Innovation and Entrepreneurship (Employment) Education Project of Guangzhou 2020PT105
6 · The paper itself

Abstract

backgroundTo investigate the epidemiological, clinical characteristics and outcomes of diabetes in pregnancy (DIP).

methodsThis single-center, retrospective study included 16,974 pregnant women hospitalized during 2018-2019. Among them, 2860 DIP patients were grouped according to diabetes type, glycemic status, and insulin use. Multivariate logistic regression analysis was conducted.

resultsThe incidence of DIP [17.10%; pregestational diabetes mellitus (PGDM), 2.00% (type I, 0.08%; type 2, 1.92%); gestational diabetes mellitus (GDM), 14.85% (GDM A1, 13.58%; GDM A2, 1.27%)] increased annually. Premature birth, congenital anomalies, large for gestational age (LGA), neonatal asphyxia, neonatal intensive care unit transfer, hypertension, and puerperal infection were more common in DIP than in healthy pregnancies. The most common comorbidities/complications were hypertension, thyroid dysfunction, cervical incompetence, intrahepatic cholestasis, premature membrane rupture, oligo/polyhydramnios, and fetal distress. GDM incidence at ages ≥35 and ≥ 45 years was 1.91 and 3.26 times that at age < 35 years, respectively. If only women with high-risk factors were screened, 34.8% GDM cases would be missed. The proportion of insulin use was 14.06% (PGDM, 55%; GDM, 8.53%). Mean gestational age at peak insulin dose in DIP was 32.87 ± 5.46 weeks. Peak insulin doses in PGDM and GDM were 3.67 and 2 times the initial doses, respectively. The risks of LGA, premature birth, cesarean section, and neonatal hypoglycemia in PGDM were 1.845, 1.533, 1.797, and 1.368 times of those in GDM, respectively. The risks of premature birth and neonatal hypoglycemia in women with poor glycemic control were 1.504 and 1.558 times of those in women with good control, respectively.

conclusionsThe incidence of adverse outcomes in DIP is high.

Indexed as

Diabetes, GestationalHypertensionHypoglycemiaInfant, Newborn, DiseasesPregnancy ComplicationsPregnancy in DiabeticsPremature BirthAdultCesarean SectionFemaleHumansInfant, NewbornInsulinMiddle AgedPregnancyPregnancy OutcomeInsulinClinical characteristicDiabetesInsulinPregnancyPregnancy outcome

Identifiers

PMID35585514
PMCPMC9118638
OpenAlexW4280621033

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.