Evidence map›Paper›PMID 35585334›Full record

Trial reportJournal of neurology2022

New remote cerebral microbleeds in acute ischemic stroke: an analysis of the randomized, placebo-controlled WAKE-UP trial.

Tim Bastian Braemswig, Jan Vynckier, Märit Jensen, Florent Boutitie, Ivana Galinovic, Claus Z Simonsen, Bastian Cheng, Tae-Hee Cho, Jan F Scheitz, Jens Fiehler and 14 more

Open access · hybridAbstract readLetterRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 10 institutions in 7 countries.

Tim Bastian BraemswigKlinik und Hochschulambulanz für Neurologie, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany. tim-bastian.braemswig@charite.de.ORCID http://orcid.org/0000-0001-6112-2800
Jan VynckierNeurology Department, Head of Stroke Unit, Moorselbaan 164, 9300, Aalst, Belgium.ORCID https://orcid.org/0000-0001-5338-961X
Märit JensenKlinik und Poliklinik Für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.ORCID https://orcid.org/0000-0001-7793-0941
Florent BoutitieService de Biostatistique, Hospices Civils de Lyon, Lyon, France.
Ivana GalinovicCenter for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Claus Z SimonsenDepartment of Neurology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0003-1363-0266
Bastian ChengKlinik und Poliklinik Für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Tae-Hee ChoDepartment of Stroke Medicine, Université Claude Bernard Lyon 1, and Hospices Civils de Lyon, Lyon, France.
Jan F ScheitzKlinik und Hochschulambulanz für Neurologie, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.
Jens FiehlerDepartment of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID https://orcid.org/0000-0001-8533-7478
Josep PuigDoctor Josep Trueta University Hospital, Department of Radiology (IDI), Girona Biomedical Research Institute (IDIBGI), Girona, Spain.
Vincent ThijsDepartment of Neurology, Austin Health, Heidelberg, Australia.ORCID https://orcid.org/0000-0002-6614-8417
Jochen B FiebachCenter for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-7936-6958
Keith W MuirInstitute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.
Norbert NighoghossianDepartment of Stroke Medicine, Université Claude Bernard Lyon 1, and Hospices Civils de Lyon, Lyon, France.
Martin EbingerCenter for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Salvador PedrazaDoctor Josep Trueta University Hospital, Department of Radiology (IDI), Girona Biomedical Research Institute (IDIBGI), Girona, Spain.ORCID https://orcid.org/0000-0003-2517-4413
Götz ThomallaKlinik und Poliklinik Für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Christian GerloffKlinik und Poliklinik Für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Matthias EndresKlinik und Hochschulambulanz für Neurologie, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.
Robin LemmensDepartment of Neurology, University Hospitals Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-4948-5956
Ludwig SchlemmKlinik und Hochschulambulanz für Neurologie, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-4165-2366
Christian H NolteKlinik und Hochschulambulanz für Neurologie, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0001-5577-1775
WAKE-UP Investigators
Humboldt-Universität zu Berlin · DEUniversität Hamburg · DEUniversité Claude Bernard Lyon 1 · FRGerman Center for Neurodegenerative Diseases · DEInstitut d'Investigació Biomèdica de Girona · ESAarhus University Hospital · DKOnze Lieve Vrouwziekenhuis Hospital · BEThe University of Melbourne · AUUniversity of Glasgow · GBVIB-KU Leuven Center for Brain & Disease Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain IschemiaIschemic StrokeStrokeCerebral HemorrhageHumansMagnetic Resonance Imaging

Identifiers

PMID35585334
PMCPMC9468109
OpenAlexW4280542247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.